Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery. The primary outcome is emergence agitation assessed using the Pediatric Anesthesia Emergence Delirium (PAED) scale. Secondary outcomes include hemodynamic parameters, induction time, recovery time, and adverse events.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sevoflurane 8% Group | Active Comparator | Participants received 8% sevoflurane inhalation for anesthesia induction via face mask. |
|
| Sevoflurane 6% Group | Experimental | Participants received 6% sevoflurane inhalation for anesthesia induction via face mask. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sevoflurane | Drug | Sevoflurane inhalation anesthesia was used for induction and maintenance of general anesthesia in pediatric patients undergoing minor ophthalmic surgery. |
|
| Measure | Description | Time Frame |
|---|---|---|
| PAED score | Measured using the Pediatric Anesthesia Emergence Delirium (PAED) scale. The PAED scale ranges from 0 to 20, with higher scores indicating more severe emergence delirium (worse outcome). | Within 30 minutes after recovery |
| Measure | Description | Time Frame |
|---|---|---|
| Induction time | Time from face mask placement to loss of eyelash reflex, measured in seconds. | Immediately after anesthesia induction |
| Recovery time | Time from discontinuation of sevoflurane to full recovery of consciousness, measured in minutes. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Laiwen Lv, MSc. | Contact | 13750440405 | llw@jsiec.org |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong | Recruiting | Shantou | Guangdong | 515041 | China |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D017043 | Chalazion |
| ID | Term |
|---|---|
| D003560 | Cysts |
| D009369 | Neoplasms |
| D005141 | Eyelid Diseases |
| D005128 | Eye Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D000077149 | Sevoflurane |
| ID | Term |
|---|---|
| D008738 | Methyl Ethers |
| D004987 | Ethers |
| D009930 | Organic Chemicals |
| D006845 | Hydrocarbons, Fluorinated |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Immediately after anesthesia discontinuation |
| Minimum alveolar concentration (MAC) | Minimum alveolar concentration (MAC) values recorded during anesthesia maintenance. | Perioperatively |
| Respiratory depression | Incidence of respiratory depression recorded during the perioperative period. | Perioperatively |
| Hypoxia | Incidence of hypoxia recorded during the perioperative period. | Perioperatively |
| Cough | Incidence of cough recorded during the perioperative period. | Perioperatively |
| Nausea and vomiting | Incidence of nausea and vomiting recorded during the postoperative recovery period. | Immediately after anesthesia until discharge |
| D006846 |
| Hydrocarbons, Halogenated |
| D006838 | Hydrocarbons |