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This randomized clinical trial aims to evaluate labial bone plate changes following immediate implant placement in Type II extraction sockets using two different xenograft materials and de-epithelialized free gingival graft in the esthetic zone . Patients requiring extraction and immediate implant placement will be randomly allocated into two groups according to the xenograft material used for defect grafting. Clinical and radiographic outcomes will be assessed to determine dimensional bone changes and implant success
Immediate implant placement in the esthetic zone has become a predictable treatment modality aiming to reduce treatment time while preserving alveolar bone and soft tissue architecture. However, dimensional alterations of the labial bone plate remain a clinical concern, particularly in Type II extraction sockets.
The present randomized controlled clinical trial will compare the effect of two different xenograft materials and de-epithelialized free gingival graft used for defect grafting during immediate implant placement. Eligible patients indicated for tooth extraction and immediate implant placement will be randomly assigned into two parallel groups based on the grafting material used.
Clinical evaluation and standardized radiographic assessment using CBCT will be performed to measure labial plate thickness changes, peri-implant bone stability, and implant success outcomes over a defined follow-up period. The findings of this study aim to provide clinical evidence regarding the most effective xenograft material for preserving peri-implant hard tissue contours in the esthetic zone
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Medpark S1 xenograft | Experimental | Patients undergoing immediate implant placement in Type II extraction sockets with defect grafting using Medpark S1 xenograft . |
|
| bio-Oss xenograft | Experimental | Patients undergoing immediate implant placement in Type II extraction sockets with defect grafting using bio-Oss xenograft. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Immediate Implant Placement with Medpark S1 xenograft | Procedure | Immediate implant placement in Type II extraction sockets, with gap grafting using Medpark S1 xenograft . |
|
| Measure | Description | Time Frame |
|---|---|---|
| Labial Bone Plate Thickness Change | Dimensional changes of the labial alveolar bone plate will be measured using standardized CBCT images to assess the effectiveness of the two xenograft materials in preserving bone contour | 6 months post-implant placement |
| Measure | Description | Time Frame |
|---|---|---|
| Peri-implant mucosal level (PML) | Intraoral scanning will be performed preoperative, immediate postoperative (baseline) and six months postoperatively. The 3D software will be used to align the baseline and six month models using the best-fit algorithm of the software to perfect the superimposition process. The superimposed models will be assessed using specific software, where the measurements will be performed to compare soft tissue outcomes between the two xenograft materials |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical assessment of Pink Esthetic score | Seven variables will be scored: mesial papilla, distal papilla, to curvature of the facial mucosa, level of the facial mucosa and soft tissue color, and texture of facial gingiva at the implant site. A score of 0, 1, or 2 will be given to each parameter obtain a final score of 14 minimum score 0,maximum score 14 higher score means better | 6 months post-implant placement |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Basma Gamal, BDS | Contact | +20 10 10231477 | basmagamal816@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry, Alexandria University, Egypt | Recruiting | Alexandria | Egypt |
This study is a randomized clinical trial designed to evaluate labial bone plate preservation following immediate implant placement in Type II extraction sockets using two different xenograft materials in the esthetic zone. Eligible participants will be randomly assigned to one of two parallel groups based on the xenograft material used for gap grafting. Clinical and radiographic assessments will be conducted to monitor dimensional changes of the labial bone plate, peri-implant tissue health, and implant success over a six-month follow-up period. All procedures will be performed under standard clinical protocols at the Faculty of Dentistry, Alexandria University
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| Immediate Implant Placement with bio-Oss xenograft | Procedure | Immediate implant placement in Type II extraction sockets, with gap grafting using bio-Oss xenograft |
|
| 6 months post-implant placement |
| ID | Term |
|---|---|
| D016301 | Alveolar Bone Loss |
| ID | Term |
|---|---|
| D001862 | Bone Resorption |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D055093 | Periodontal Atrophy |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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