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The goal of this clinical trial is to compare rate and amount of space closure among fresh vs healed extraction sites during fixed orthodontic treatment in patients with all first premolar's extraction Primary outcome measure is to calculate rate and amount of space closure between fresh vs healed as well as maxilla and mandible.
The mandibular and maxillary arches of 34 patients will be included whose treatment plan decision was the extraction of all first premolars. Due to the split mouth approach, patients' maxillary and mandibular arches are randomly subdivided into two groups (right and left sides). First premolar extraction spaces in Group 1 will be closed once they have healed (6 week), while first premolar extraction spaces in Group 2 will be closed immediately after extraction. Both the upper and lower extraction spaces will be closed using coil springs (magnitude of force 30g per side). We'll specify the following time intervals: T1: Immediately prior to space closure; T2: 1 month after initial space closure; T3: 2 months after initial space closure T3: 3 months after initial space closure. Records will include measuring the rate and amount of space closure through Vernier calipers on dental cast as well as intraorally and will be evaluated at each time point.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| fresh vs healed extraction socket | Experimental | Comparison of rate and amount of space closure in fresh vs healed extraction socket |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Space Closure | Procedure | Space Closure in fresh vs healed extraction socket |
|
| Measure | Description | Time Frame |
|---|---|---|
| To compare rate of space closure among fresh vs healed extraction sites during fixed orthodontic treatment in patients with all first premolar's extraction. | This study will be useful in making the timely decision for extraction of premolars and estimation of orthodontic treatment duration as well. | four time points are taken. T0: Baseline, T1: One month, T2: Two months, T3: Three months |
| Measure | Description | Time Frame |
|---|---|---|
| To compare amount of space closure among fresh vs healed extraction sites during fixed orthodontic treatment in patients with all first premolar's extraction. | Total space closure | Space closure at T3 is subtracted from T0 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Sadia Rizwan, BDS, FCPS, CHPE | Dr Ishrat ul Ebad Khan Institute of Oral Health Sciences | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dr Ishrat ul Ebad Khan Institute of Oral Health Sciences | Karachi | Sindh | 75300 | Pakistan |
There is no need to share individual participants data
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| ID | Term |
|---|---|
| D000082882 | Bicuspid Aortic Valve Disease |
| ID | Term |
|---|---|
| D006330 | Heart Defects, Congenital |
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D006331 | Heart Diseases |
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| ID | Term |
|---|---|
| D019516 | Orthodontic Space Closure |
| ID | Term |
|---|---|
| D009971 | Orthodontics, Corrective |
| D009970 | Orthodontics |
| D003813 | Dentistry |
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Each patients mouth is splitted into four quadrants.Intervention is done either on left or right side randomly allocated
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| D000082862 | Aortic Valve Disease |
| D006349 | Heart Valve Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |