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Cancer-related fatigue (CRF) is a common and debilitating symptom in patients with cancer. Evidence-based non-pharmacological approaches include sleep hygiene, physical activity, nutritional management, and traditional Chinese medicine (TCM). This study evaluates the clinical effectiveness of an interdisciplinary holistic program integrating Chinese and Western therapies for CRF among hospitalized cancer patients receiving integrated care. Approximately 100 participants will be enrolled and followed for up to 3 months.
Eligible hospitalized cancer patients receiving integrated Chinese and Western care will be enrolled after providing informed consent. Participants will complete a CRF questionnaire and receive a non-invasive holistic integrative care program, including patient education, sleep hygiene, exercise guidance, nutritional assessment/intervention, and TCM-related care. The primary endpoint is change in CRF score. Secondary endpoints include TCM constitution assessment, vital signs, anthropometrics, complete blood count, and liver/renal function tests. Participants will be followed for 3 months from enrollment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Integrated Chinese and Western Holistic Care | Experimental | All participants receive an integrated Chinese and Western holistic care program during hospitalization for cancer-related fatigue management. The program includes routine fatigue assessment and individualized supportive care measures (education, sleep hygiene, exercise encouragement, aromatherapy and/or massage, nutrition consultation, and shared decision-making). Traditional Chinese Medicine consultation (e.g., acupuncture and/or Chinese herbal medicine) may be provided when clinically indicated. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Integrated Chinese and Western Holistic Care Program | Other | An interdisciplinary integrative care program combining Western supportive care and Traditional Chinese Medicine to manage cancer-related fatigue in hospitalized oncology patients. Core components include fatigue assessment, patient education and symptom management guidance, sleep hygiene, exercise encouragement, aromatherapy and/or massage, nutrition assessment and counseling, and shared decision-making. Traditional Chinese Medicine consultation may provide acupuncture and/or Chinese herbal medicine according to patient needs and clinical judgment. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Cancer-Related Fatigue (CRF) Score (0-10) | CRF is assessed using the Taiwan Society of Cancer Palliative Medicine fatigue scale (0-10) during hospitalization. Peak CRF score is defined as the maximum recorded CRF score from admission to discharge. Discharge CRF score is defined as the last in-hospital CRF assessment prior to discharge. The primary outcome is the within-participant change in CRF score from peak to discharge. | From admission (baseline) through discharge (last in-hospital assessment; up to 30 days) |
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of Participants With Moderate-to-Profound CRF at Discharge (CRF Score ≥4) | Percentage of participants whose discharge CRF score is ≥4 (moderate or above) on the Taiwan Society of Cancer Palliative Medicine fatigue scale (0-10). | At discharge (last in-hospital assessment; up to 30 days after admission) |
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Inclusion Criteria:
Signed informed consent form.
Age 20 to 95 years.
Receiving integrated Chinese and Western holistic care.
Agree to provide clinically relevant data for this study.
Exclusion Criteria:
Refuse to continue participation during the study period, or the family requests discontinuation (withdrawal).
Psychiatric disorder that makes the participant unable to cooperate.
Exclusion Criteria:
-
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Taichung Tzu Chi Hospital | Taichung | 42743 | Taiwan |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D000070263 | Sleep Hygiene |
| ID | Term |
|---|---|
| D015438 | Health Behavior |
| D001519 | Behavior |
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Single-group, nonrandomized, open-label, quasi-experimental evaluation of an interdisciplinary holistic care program for hospitalized adult patients with cancer-related fatigue. The program integrates nursing education, sleep hygiene (optional aromatherapy), exercise promotion, dietician consultation, and Traditional Chinese Medicine modalities.
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| Distribution of CRF Severity Categories at Discharge (0, 1-3, 4-6, 7-8, 9-10) |
Distribution of discharge CRF scores categorized as 0, 1-3, 4-6, 7-8, and 9-10 on the Taiwan Society of Cancer Palliative Medicine fatigue scale. |
| At discharge (last in-hospital assessment; up to 30 days after admission) |