Drug Coated Balloon vs. Drug-eluting Stent in Patients With Coronary Artery Disease

Drug Coated Balloon vs. Drug-eluting Stent in Patients With Coronary Artery Disease

Studies exploring the feasibility of drug-eluting balloon (DCB) in de-novo coronary lesions are limited. There are scarce data comparing DCB with drug-eluting stent (DES) in patients with high bleeding risk (HBR), a situation in which long-term maintenance of dual antiplatelet therapy (DAPT) is a clinical dilemma. This target trial emulation aims to compare clinical outcomes between DCB angioplasty and conventional DES implantation in de-novo coronary lesions in patients with coronary artery disease.

Inclusion Criteria:

• Patients with coronary artery disease undergoing percutaneous coronary intervention
• Used devices number less than three (relatively simple lesion)

Exclusion Criteria:

• Hybrid strategy (DCB and DES use)
• Failed percutaneous coronary intervention
• Previous revascularization procedure before index percutaneous coronary intervention