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This study aims to compare the clinical outcomes of bilateral alveolar cleft reconstruction using double iliac corticocancellous bone block grafts versus conventional autogenous particulate bone grafting. The study will evaluate graft stability, bone volume, and postoperative complications in patients with bilateral alveolar clefts. Participants will be allocated into two groups, each receiving one of the two grafting techniques. Clinical and radiographic assessments will be performed during follow-up to determine the effectiveness and predictability of each method
Alveolar cleft reconstruction is a critical component in the comprehensive management of patients with cleft lip and palate, aiming to restore alveolar continuity, facilitate tooth eruption, and provide support for the nasal base. Autogenous bone grafting remains the gold standard for alveolar cleft repair, with the iliac crest being the most commonly used donor site due to its rich cancellous bone content.
Conventional particulate cancellous bone grafting has been widely used with predictable outcomes; however, it may be associated with graft resorption and reduced structural stability, particularly in bilateral alveolar cleft cases. Recently, the use of corticocancellous bone block grafts has been proposed to enhance graft stability, maintain volume, and improve overall outcomes.
This study aims to compare double iliac corticocancellous bone block grafts with conventional autogenous particulate bone grafting in the reconstruction of bilateral alveolar clefts. Patients diagnosed with bilateral alveolar clefts and meeting the inclusion criteria will be enrolled and allocated into two groups. One group will receive double iliac corticocancellous bone block grafts, while the other will undergo reconstruction using conventional particulate bone grafting techniques.
Clinical and radiographic evaluations will be performed to assess graft stability, bone volume, and postoperative complications. Follow-up assessments will be conducted at predefined intervals to evaluate the success and predictability of each technique. The findings of this study are expected to provide evidence regarding the most effective grafting approach for bilateral alveolar cleft reconstruction
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Double Iliac Corticocancellous Bone Block Graft | Experimental | Participants will undergo bilateral alveolar cleft reconstruction using double iliac corticocancellous bone block grafts harvested from the iliac crest |
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| Conventional Autogenous Particulate Bone Graft | Active Comparator | Participants will undergo bilateral alveolar cleft reconstruction using conventional autogenous particulate bone graft harvested from the iliac crest. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Iliac Corticocancellous Bone Block Graft | Procedure | participants will undergo bilateral alveolar cleft reconstruction using double iliac corticocancellous bone blocks harvested from the iliac crest. The grafts will be secured to premaxilla by micro screws to restore alveolar continuity, facilitate tooth eruption, and improve bone volume |
| Measure | Description | Time Frame |
|---|---|---|
| bone volume | Measurement of alveolar bone volume using radiographic imaging (CBCT) to compare bone maintenance between the two techniques | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mahmoud Samy Abdelmoniem, PhD Researcher | Contact | 0020201002752193 | mhsamy.ms@gmail.com | |
| mohamed omara, associate professor | Contact | 0020201144452862 | mohammed.omara@dentistry.cu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Mahmoud Samy Abdelmoniem, PhD researcher | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Dentistry, Cairo University | Cairo | Cairo Government | 12613 | Egypt |
Individual participant data (IPD) will not be shared. The study data will be used only for research purposes and will not be made publicly available
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Participants will be randomly assigned into two parallel groups. The first group will undergo bilateral alveolar cleft reconstruction using double iliac corticocancellous bone block grafts, while the second group will receive conventional autogenous particulate bone grafting. Clinical and radiographic outcomes will be compared between both groups
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| Autogenous Particulate Bone Graft | Procedure | participants will undergo bilateral alveolar cleft reconstruction using conventional autogenous particulate bone graft harvested from the iliac crest. The graft material will be packed into the alveolar defect to restore bone continuity and support future tooth eruption. |
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