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The goal of this qualitative study is to identify and better understand the symptoms of stricturing Crohn's disease in order to inform the development of more appropriate clinical evaluation scores. This study focuses on adult patients diagnosed with stricturing Crohn's disease who are followed in hospital gastroenterology departments.
The main questions it aims to answer are:
Participants will:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Semi-structured interview | Other | One-hour semi-structured interview in person or by videoconference. Interviews will be audio-recorded, pseudonymized, transcribed, and analyzed, and participants can review their transcripts before final anonymization. |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of patient-reported symptom categories associated with stenosing Crohn's disease, derived from thematic content analysis of single semi-structured interviews. | Up to 5 months |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of patient-reported symptom categories described as early warning signs of a stenosing flare, derived from qualitative content analysis of individual interviews. | Up to 5 months | |
| Frequency of patient-reported daily life impact domains identified through qualitative content analysis of individual interviews. |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patient (≥ 18 years old), with a confirmed diagnosis of Crohn's disease presenting a stricturing form of the disease
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zahra Moussavi | Contact | +33 4 76 76 86 41 | zmoussavi@chu-grenoble.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Grenoble Alpes | La Tronche | 38700 | France |
Individual Participant Data (IPD) will not be shared due to the qualitative nature of the study. The data consist of interview transcripts containing health-related information and sensitive personal content. Full anonymization cannot be guaranteed, and data sharing was not covered by the informed consent or the European regulatory framework (GDPR) applicable to this study.
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| ID | Term |
|---|---|
| D003424 | Crohn Disease |
| ID | Term |
|---|---|
| D015212 | Inflammatory Bowel Diseases |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| Up to 5 months |
| Frequency of patient-reported mental health impact domains identified through qualitative content analysis of individual interviews. | Up to 5 months |
| Frequency of patient-reported quality-of-life impact domains identified through qualitative content analysis of single semi-structured interviews. | Up to 5 months |
| Frequency of patient-reported coping strategy categories identified through qualitative content analysis of individual interviews. | Up to 5 months |
| D007410 | Intestinal Diseases |