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| ID | Type | Description | Link |
|---|---|---|---|
| R01AG098263 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Aging (NIA) | NIH |
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The goal of this clinical is to learn how the brain supports different kinds of memory decisions in healthy young and older adults. The main question it seeks to answer is: Do older adults make memory decisions by integrating across experiences?
Young (aged 18-30 years) and older (aged 65-80 years) participants will complete a memory task while undergoing functional MRI to measure their brain responses.
Researchers will compare brain measures of integration in older adults to those of young adults to see if integration increases in older age.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental Arm | Experimental | This is a within-subject design with a single experimental arm |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Memory decision type | Behavioral | Subjects will be probed to either remember an association they saw directly during the study phase or to make an inference across indirectly associated items. |
| Measure | Description | Time Frame |
|---|---|---|
| Behavioral memory responses | Participants will complete the study and test phases of a memory-based inference task designed by the investigators. The investigators will focus on the accuracy of decisions (0-100% scale with higher scores meaning better memory) and how long it takes to make correct decisions (in seconds, faster responses mean less cognitive processing needed). | Session 2 (experimental session) |
| Neural memory responses | Investigators will measure the neural underpinnings of direct memory and the ability to make inferences. | Session 2 (experimental session) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Caitlin Bowman, PhD | Contact | 414-251-5010 | bowman2@uwm.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Wisconsin-Milwaukee | Recruiting | Milwaukee | Wisconsin | 53211 | United States |
Shared data will include structural and function MRI images, behavioral data from experimental tasks, behavioral data from the pre-experimental cognitive assessment, behavioral data from any post-experimental debriefing questionnaires, and participant demographic information.
Data from each experiment will be made available upon acceptance of the first manuscript resulting from the project or at the end of the award period (whichever comes first for a given experiment). Investigators expect the data to be available indefinitely.
The investigators will publicly share all de-identified data through OpenNeuro. Access to the data will not be controlled.
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