The study investigates the use of high-flow oxygen therapy devices in patients at higher risk of complications during sedated digestive endoscopies. Sedation controlled by the endoscopist improves patient tolerance and facilitates higher-quality procedures, but it can have side effects such as hypoxemia or respiratory depression, especially in patients with sleep apnea, obesity, lung diseases, those over 60 years old, or with a history of sedation complications. While preventive measures, such as oxygen administration, are taken, the study aims to compare the effectiveness of new high-flow oxygen therapy devices with conventional nasal cannulas to improve safety during endoscopies.

Inclusion Criteria:

• Be ≥ 18 years old
• Sign the Informed Consent
• Obesity (BMI ≥ 30 kg/m²)
• ASA III
• Stable pulmonary disease (no hospitalization in the last 6 months)
• Stable heart failure (no hospitalization in the last 6 months)
• Diagnosed or suspected obstructive sleep apnea with a score ≥ 3 on the STOP-Bang scale (APPENDIX II)
• History of sedation-related complications in a previous ESP.

Exclusion Criteria:

• ASA IV patients
• Worsening heart failure at the time of the endoscopy or unstable (hospitalized < 6 months)
• Worsening respiratory disease at the time of the endoscopy or unstable (hospitalized < 6 months)
• Pregnant women
• Use of home oxygen therapy
• Patients with orotracheal intubation
• Tracheostomized patients
• Patients allergic to or unable to use propofol

Individual participant data will not be shared. The data will be pseudonymized to ensure privacy and will only be accessible to the research team directly involved in the study.