A Study of ORN252 in Healthy Participants

A Phase 1 Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ORN252 in Healthy Participants

The purpose of this study is to assess the safety and tolerability of ORN252 in healthy adult participants.

Inclusion Criteria:

• Male and female participants who are healthy as determined by the Investigator based on review of medical history, physical examination, and laboratory tests
• Participant is willing and able to comply with study visits and other protocol requirements
• Other protocol specific inclusion criteria may apply

Exclusion Criteria:

• Clinically significant history or presence of organ dysfunction
• Use of any investigational product within 3 months, or 5 half-lives, whichever longer
• Other protocol specific exclusion criteria may apply