Reproductive Prognosis in Women Seeking Offspring After Medical or Surgical Therapy for Endometriosis

La Prognosi Riproduttiva Nelle Donne Che Ricercano Prole Dopo Terapia Medica o Chirurgica Per Endometriosi: Studio Multicentrico Italiano

The study aims to compare the percentage of women with endometriosis who undergo PMA after medical vs surgical treatment and to describe conception patterns, pregnancy rates, and number of live vessels in women seeking offspring with endometriosis.

The objective of the study is to compare how many women with endometriosis undergo PMA after medical treatment and how many after surgical treatment , then compare these data with those reported in the literature. Secondary objectives will be to describe the mode of conception ande pregnancy rate and to compare the pregnancy rate from post-surgical PMA observed in the present Italian multicenter study with that observed in the previous single-center study conducted at the Foundation. This will allow to evaluate the impact of 15 years of evolution of surgical and PMA techniques on the reproductive prognosis of women operated for endometriosis and to expand the observation to the whole Italian territory.

Inclusion Criteria:

• age <40 years at the time of offspring research
• previous ultrasound or surgical diagnosis of endometriosis made in one of the endometriosis referral centres participating in the study
• search for offspring after diagnosis
• consent to the use of pseudonymised data for research purposes.

Exclusion Criteria:

• women without endometriosis
• age >=40 years at the time of the search for offspring
• women who have undergone demolition surgery
• women who do not wish to have offspring
• women who have not given consent for their pseudonymised data to be used for research purposes
• severe male infertility factor (testicular sperm retrieval)