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The study aims to compare the percentage of women with endometriosis who undergo PMA after medical vs surgical treatment and to describe conception patterns, pregnancy rates, and number of live vessels in women seeking offspring with endometriosis.
The objective of the study is to compare how many women with endometriosis undergo PMA after medical treatment and how many after surgical treatment , then compare these data with those reported in the literature. Secondary objectives will be to describe the mode of conception ande pregnancy rate and to compare the pregnancy rate from post-surgical PMA observed in the present Italian multicenter study with that observed in the previous single-center study conducted at the Foundation. This will allow to evaluate the impact of 15 years of evolution of surgical and PMA techniques on the reproductive prognosis of women operated for endometriosis and to expand the observation to the whole Italian territory.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PMA | Other | use of Medically assisted procreation techniques (PMA) |
| Measure | Description | Time Frame |
|---|---|---|
| endometriosis and PMA | Compare the number of women who undergo PMA after medical treatment with those who undergo PMA after surgery, then compare these data with those reported in the literature | 2012 to 2021 diagnosis |
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Inclusion Criteria:
Exclusion Criteria:
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Women with endometriosis with an ultrasound or surgical diagnosis of endometriosis in one of the centres participating in the study who sought a pregnancy after diagnosis at an age of less than 40 years.
The number of patients required will be approximately 650 in order to detect an absolute difference of ≥10% between the two groups ( medical or surgery terapy)..
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Nicola Dr Berlanda, principal investigator | Contact | +39 0255031 | nicola.berlanda@policlinico.mi.it |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico | Recruiting | Milan | MI, Italia | 20077 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18394620 | Result | Somigliana E, Daguati R, Vercellini P, Barbara G, Benaglia L, Crosignani PG. The use and effectiveness of in vitro fertilization in women with endometriosis: the surgeon's perspective. Fertil Steril. 2009 May;91(5):1775-9. doi: 10.1016/j.fertnstert.2008.02.004. Epub 2008 Apr 3. |
| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D004715 | Endometriosis |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| D000091662 | Genital Diseases |