This study done at the psychiatrics hospital of the cross Lebanon examined whether guided meditation combined with special sound stimulation (binaural beats) could help reduce negative symptoms of schizophrenia, such as low motivation and social withdrawal. Ninety inpatients participated in a six-week program and were assigned to meditation alone or meditation combined with either alpha- or theta-frequency sound stimulation.

Results showed that patients who received meditation with binaural beats improved more than those who had meditation alone. The greatest improvement was seen in the theta-frequency group. Although not all differences were statistically significant, the findings suggest that this simple, low-cost, non-medication approach may help reduce persistent negative symptoms. Larger studies are needed to confirm these results.

Schizophrenia is a mental health condition that can cause a wide range of symptoms. While medications often help reduce positive symptoms such as hallucinations or delusions, many patients continue to experience "negative symptoms," like reduced motivation, limited emotional expression, and social withdrawal. These symptoms can have a major impact on daily life and are often harder to treat. Recent research suggests that mind-body interventions, such as meditation and specific sound-based techniques called binaural beats, can influence brain activity linked to attention, memory, and emotional regulation. Alpha and theta brainwave patterns are often disrupted in people with schizophrenia, which may contribute to negative symptoms.

This study, conducted at the psychiatric hospital of the cross in Lebanon, explored whether pairing guided meditation with frequency-specific binaural beats could help reduce negative symptoms in patients with schizophrenia. The study also compared two types of sound frequencies-alpha and theta-to see which might be more effective. Ninety stable inpatients diagnosed with schizophrenia participated in the study. They were randomly assigned to one of three groups: Guided meditation alone, Meditation plus alpha-frequency binaural beats, Meditation plus theta-frequency binaural beats. Participants attended sessions regularly over six weeks. Their symptoms were measured before and after the program using validated Arabic clinical scales. Patients who received meditation combined with binaural beats showed greater improvement in negative symptoms compared to those who received meditation alone. The most notable improvements were seen in the theta-frequency group, which also appeared more engaged during the sessions. However, individual responses varied, and not all differences between groups were statistically significant. Mind-body approaches like meditation and binaural beats may offer new ways to support patients with schizophrenia, helping improve motivation, emotional engagement, and overall quality of life-without relying solely on medication.

Inclusion Criteria:

• Hospitalized patients at the psychiatrics hospital of the cross
• Aged between 18 and 65 years
• Diagnosed with schizophrenia according to the diagnostic and statistical manual of mental disorders, fifth edition (DSM-5)
• Clinically stable, receiving a consistent dose of antipsychotic medication for at least 3 months before recruitment

Exclusion Criteria:

• Acute psychiatric symptoms requiring immediate intervention or hospitalization
• Current diagnosis of substance use disorder
• Documented history of non-compliance with medical treatment
• Hearing impairments that could affect accurate perception of auditory stimuli such as binaural beats

No, individual participant data will not be shared with other researchers, due to the sensitive nature of psychiatric patient information and the need to ensure participant confidentiality and privacy.

This study was double-blinded. Both the participants and the principal investigator were blinded to group allocation to minimize expectancy and placebo effects. Only the study coordinator responsible for randomization and session assignment was aware of group allocation.