Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The goal of this study is to learn whether virtual reality (VR) construction tasks can detect performance changes associated with prior sleep, and to determine the extent to which these changes can be distinguished from interacting repetitively with VR itself.
After passing a physical assessment and psychological screen, up to 12 participants will be enrolled. Ahead of each 8-hour in-laboratory assessment, participants will be asked to participate in a 1-week at-home monitoring period while continuing with their regular sleep/wake schedule. During this at-home assessment participants will be asked to wear an ActiGraph to objectively assess sleep and complete daily sleep diaries and call into a time-stamped voice-mailbox when going to bed and getting out of bed to confirm sleep/wake times. Participants will be asked to refrain from any alcohol, substances, or intense physical activity during each 1-week at home monitoring period. Similarly, participants are asked to refrain from caffeine consumption 5h prior to the in lab. Participants will then participate in two 8-hour sessions in an in-laboratory setting with a 1-week washout period in-between each in-laboratory visit. The two 8-hour visits will be identical in schedule and instrumentation, differing only in whether VR tasks are administered. Order of visits will be randomized. At each visit, participants will arrive to the laboratory ~6h after their habitual waketime (determined from daily call-ins) and be hooked up for ECG and beat-by-beat blood pressure. They will wear an ActiGraph the entire in-laboratory visit. Participants will also be asked to complete the Karolinska Sleepiness Scale (KSS) questionnaire and the modified Positive Affect-Negative Affect Schedule (PANAS) and the Profile of Mood States (POMS) questionnaire. Finally, participants will be asked to complete construction virtual reality tasks using a virtual reality headset during each of the 4 time points at each visit.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Construction Virtual Reality Stress Challenges | Experimental | Participants will be randomly assigned to a laboratory visit that will contain construction virtual reality stress challenges. |
|
| No Construction Virtual Reality Stress Challenges | Experimental | Participants will be randomly assigned to a laboratory visit that will not contain construction virtual reality stress challenges. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Construction Virtual Reality Stress Challenges | Other | Participants will be randomly assigned to a laboratory visit that will contain construction virtual reality stress challenges. |
| Measure | Description | Time Frame |
|---|---|---|
| Feasibility: Recruitment | Number of eligible participants who enroll in the study. | From first date of recruitment activities to last day of study activities, up to 100 weeks. |
| Feasibility: Retention | Proportion of eligible participants who enroll and complete all scheduled study visits. | From start of recruitment activities to the end of study activities, up to 100 weeks. |
| Feasibility: Tolerability of Repeated VR use and Physiologic Monitoring | Proportion of participants able to complete repeated VR tasks and physiologic monitoring without early discontinuation due to discomfort, cybersickness, or adverse symptoms. | Assessed each 8-hour in laboratory visit |
| Feasibility: Data Completeness and Quality | Proportion of planned VR task sessions and physiologic recordings successfully completed with usable data. | Through study completion, an average of 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Instruction Re-Engagement During VR Tasks | Number of times participants revisit or request task instructions during construction-related VR tasks. | Assessed during each 8-hour in-laboratory visit. |
| Task Resumption Time Following Disruption |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Nicole P Bowles, PhD | Contact | 503-494-2541 | bowlesn@ohsu.edu |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Oregon Health and Science University | Portland | Oregon | 97239 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Participants will be randomized to participate in construction virtual reality tasks on visit 1 or visit 2.
Not provided
Not provided
Not provided
| No Construction Virtual Reality Stress Challenges | Other | Participants will be randomly assigned to a laboratory visit that will not contain construction virtual reality stress challenges. |
|
Time (seconds) required for participants to resume task engagement following an interruption or distraction during VR tasks.
| Assessed during each 8-hour in-laboratory visit. |
| VR Task Completion Time | Time required to complete construction-related VR tasks. | Assessed during each 8-hour in-laboratory visit. |
| Movement Efficiency During VR Tasks | Movement efficiency metrics during VR tasks, including the number of movements required to manipulate objects or complete task objectives. | Assessed during each 8-hour in-laboratory visit. |
| Controller Interaction Metrics | Controller interaction characteristics during VR tasks, including grip engagement and input patterns. | Assessed during each 8-hour in-laboratory visit. |
| Gaze Behavior During VR Tasks | Gaze behavior during VR tasks assessed via eye tracking, including fixation duration and spatial distribution of gaze points. | Assessed during each 8-hour in-laboratory visit. |
| Subjective Sleepiness | The Karolinska Sleepiness Scale (KSS) with responses 1 (Extremely alert) to 10 (Extremely sleepy, can't keep awake) will assess subjective sleepiness | 4 Time Points during each 8-hour in-laboratory visit |
| Positive Affect | Positive affect assessed using the Positive Affect subscale of the Positive and Negative Affect Schedule (PANAS). The Positive Affect subscale consists of 10 items rated on a 5-point Likert scale (1 = very slightly or not at all to 5 = extremely), with total scores ranging from 10 to 50. Higher scores indicate greater positive affect. | Assessed at four time points during each 8-hour in-laboratory visit. |
| Negative Affect | Negative affect assessed using the Negative Affect subscale of the Positive and Negative Affect Schedule (PANAS). The Negative Affect subscale consists of 10 items rated on a 5-point Likert scale (1 = very slightly or not at all to 5 = extremely), with total scores ranging from 10 to 50. Higher scores indicate greater negative affect. | Assessed at four time points during each 8-hour in-laboratory visit. |
| Mood Disturbance | Mood disturbance assessed using the Profile of Mood States (POMS). The POMS evaluates multiple mood domains (e.g., tension-anxiety, depression-dejection, anger-hostility, vigor, fatigue, confusion). A Total Mood Disturbance (TMD) score is calculated by summing negative mood subscales and subtracting the vigor score. TMD scores typically range from approximately -20 to 100, depending on the version used. Higher scores indicate greater overall mood disturbance, while lower or negative scores indicate more favorable mood states. | Assessed at four time points during each 8-hour in-laboratory visit. |
| Parasympathetic activity | Assessed using the high frequency power (HF) of the HRV power spectrum (collected from cleaned ECG using Kubios) to estimate cardiac parasympathetic activity as modulated by respiratory sinus arrhythmia during the time of seated rest noted above (but first 5 minutes consistent with field standards). | Assessed during each 8-hour in-laboratory visit. |
| Systolic Blood Pressure | Will be measured beat-to-beat using a non-invasive device employing the volume-clamp method with hydrostatic correction with measures on alternating fingers every 15 min (NIBP). | Assessed during each 8-hour in-laboratory visit. |
| Diastolic Blood Pressure | Will be measured beat-to-beat using a non-invasive device employing the volume-clamp method with hydrostatic correction with measures on alternating fingers every 15 min (NIBP). | Assessed during each 8-hour in-laboratory visit. |
| Electrodermal activity | Continuously assessed using galvanic skin response (GSR) electrodes attached to a fully isolated low voltage amplifier (AD Instruments Ltd). GSR electrodes will be attached to the distal phalange of the index and middle fingers of the non-dominant hand via supplied Velcro tape. | Assessed during each 8-hour in-laboratory visit. |