Cross-sectional Study of Vitamin B6 in Parkinson's Disease

A Cross-sectional Study of Serum Vitamin B6 Levels in People Living With Parkinson's Disease

The purpose of this study is to estimate the prevalence of abnormal serum levels of vitamin B6, and the associations of those levels with demographic and clinical variables in a randomly selected sample of people living with Parkinson's disease, compared to historical controls.

Inclusion Criteria:

• People with a clinical diagnosis of Parkinson's disease according to the diagnostic criteria of the Movement Disorders Society [Postuma 2015].
• Participants are ≥ 18 years old.
• As determined by the study investigators, participants are able to communicate at a level sufficient to undergo study interviews.
• As determined by the study investigators, participants have the capacity to provide written informed consent and the ability to comply with all study procedures.

Exclusion Criteria:

• People expected to have abnormal vitamin B6 levels due to underlying conditions (renal disease, bowel disease, rheumatoid arthritis).
• People taking medications (other than levodopa) expected to interfere with B6 levels (steroids, cycloserine, hydralazine, isoniazid, theophylline, penicillamine).