Multimodal Pulmonary Rehabilitation in Radiographic Axial Spondyloarthritis

Multimodal Pulmonary Rehabilitation in Radiographic Axial Spondyloarthritis: A Prospective Pilot Study Addressing Mechanical Restriction and Functional Capacity

This prospective pilot study aims to evaluate the efficacy of a structured 8-week multimodal pulmonary rehabilitation (PR) program specifically designed for patients with radiographic axial spondyloarthritis (r-axSpA). The study assesses the impact of a composite intervention incorporating aerobic conditioning, resistance training, flexibility protocols, and targeted diaphragmatic breathing on functional exercise capacity, dyspnea severity, and pulmonary function.

Inclusion Criteria:

• Age between 18 and 75 years.
• Diagnosis of radiographic axial spondyloarthritis (r-axSpA) confirmed according to the Modified New York Criteria.
• Clinical stability without acute flares or escalation of systemic therapy in the preceding 3 months.
• Ability to perform spirometry and ambulate safely.

Exclusion Criteria:

• Primary respiratory disorders (e.g., COPD and interstitial lung disease) acting as the primary cause of limitation.
• Significant cardiovascular contraindications to exercise.
• Pregnancy.
• Participation in a structured rehabilitation program within the last 3 months.