Effectiveness and Safety of Corneal Collagen Cross Linking After Induction of Stromal Emphysema in Keratoconus

Effectiveness and Safety of Corneal Collagen Cross Linking After Induction of Stromal Emphysema in Keratoconus

in this study we evaluated the effectiveness and safety of corneal collagen cross-linking in keratoconic eyes with thin cornea after induction of stromal emphysema prior to riboflavin instillation and UV-A corneal irradiation

Inclusion Criteria:

• Progressive KC proven by clinical examination, tomography, and pachymetry
• Thinnest corneal location thickness between 390 to 450 microns

Exclusion Criteria:

• Previous ocular Trauma or Surgery.
• History of herpetic eye disease
• Central corneal scarring
• Cornea guttata
• Ocular surface disease and dry eye disease
• Vernal and atopic keratoconjunctivitis
• Cataract
• Glaucoma, intraocular pressure less than 10 or more than 21 mmHg
• Posterior segment abnormalities
• Nystagmus or other conditions that interfere with patient's fixation
• Diabetes mellitus
• pregnancy
• Collagen vascular disease, autoimmune disease and patients receiving immunosuppressive therapy