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evaluate the relationship between triphasic CT and EUS findings and the characterization of pancreatic lesions.
Comparison Between Triphasic CT and EUS-FNB in characterization of Pancreatic Lesions
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients assessed by Triphasic CT scan | Triphasic CT scan: Performed using a multidetector CT scanner and CT parameters assessed: Size, shape, and margins of the lesion Enhancement pattern (hypo / iso / hyper-enhancing) Calcifications or cystic components |
| |
| Patients assessed by Endoscopic Ultrasound (EUS)&Tissue Sampling | Performed using linear echoendoscope under conscious sedation or general anesthesia EUS-guided sampling Fine-needle aspiration (FNA) or fine-needle biopsy (FNB) using 19G/22G needles. Multiple passes obtained for cytology and histopathology. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Full clinical history (pain, jaundice, weight loss, pancreatitis history). Physical examination with focus on abdominal and systemic findings. | Diagnostic Test | Full clinical history (pain, jaundice, weight loss, pancreatitis history). Physical examination with focus on abdominal and systemic findings. |
| Measure | Description | Time Frame |
|---|---|---|
| Diagnostic accuracy of triphasic CT compared to EUS-guided biopsy in differentiating benign from malignant pancreatic lesions. | the diagnostic accuracy of triphasic CT compared to EUS-guided biopsy in differentiating benign and malignant pancreatic lesions, calculated in terms of sensitivity, specificity, PPV, NPV, and overall accuracy, using final histopathological diagnosis as the reference standard. | one year |
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Inclusion Criteria:
*Adult patients (age>18 years) presenting with focal pancreatic lesions detected on initial imaging.
Exclusion Criteria:
Previous pancreatic surgery.
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Adult patients (age>18 years) presenting with focal pancreatic lesions detected on initial imaging.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed Abdullah Ashmawy, Prof. Dr | Contact | 01005679880 | rasharma@aun.edu.eg | |
| Mohamed Mahdy, ProfDr | Contact | 01064455652 | drmohhakim@aun.edu.eg |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19803666 | Background | Iglesias Garcia J, Larino Noia J, Dominguez Munoz JE. Endoscopic ultrasound in the diagnosis and staging of pancreatic cancer. Rev Esp Enferm Dig. 2009 Sep;101(9):631-8. doi: 10.4321/s1130-01082009000900006. | |
| Background | Öztürk B, Ekmen N, et al. The diagnostic role of endoscopic ultrasonography, CT, and MRI in pancreatic cystic lesions. J Clin Med Kaz. 2021;18(4):71-80. | ||
| Background | Chen J, Sahai AV, et al. Diagnostic accuracy of endoscopic ultrasound-guided fine-needle aspiration in pancreatic tumors. BMC Gastroenterol. 2012;12:125. | ||
| 38201387 |
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|
| Result |
| Chatterjee A, Shah J. Role of Endoscopic Ultrasound in Diagnosis of Pancreatic Ductal Adenocarcinoma. Diagnostics (Basel). 2023 Dec 28;14(1):78. doi: 10.3390/diagnostics14010078. |
| ID | Term |
|---|---|
| D010147 | Pain Measurement |
| ID | Term |
|---|---|
| D009460 | Neurologic Examination |
| D010808 | Physical Examination |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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