This randomized controlled study was conducted to determine the effect of music played during the angiography procedure on patients' anxiety levels and vital signs. Patients scheduled for angiography were randomly assigned to either a music intervention group or a control group receiving routine care. Anxiety levels were assessed using validated anxiety measurement tools, and vital signs including blood pressure, heart rate, and oxygen saturation were recorded at multiple time points before, during, and after the procedure. In the intervention group, selected music was played throughout the angiography procedure, while no music intervention was applied to the control group. This study evaluates the role of music as a non-pharmacological intervention for anxiety management during angiography.

This study was conducted to determine the effect of music played during the angiography procedure on patients' anxiety levels and vital signs. The study was designed as a quantitative, experimental, pretest-posttest randomized controlled trial. Stratified randomization was applied, and patients were assigned to groups according to risk factors including physician, gender, and age. The randomization process was carried out in accordance with the principle of probabilistic assignment using a computer-assisted randomization method.

The study was conducted between June 2025 and November 2025 with patients who applied to the cardiology outpatient clinic of a private hospital and were scheduled to undergo angiography. Research data were collected using a Personal Information Form, the Hospital Anxiety Subscale of the Hospital Anxiety and Depression Scale, the Distress Thermometer, and a Vital Signs Monitoring Form. All data collection forms were administered together with the informed consent form.

After preoperative electrocardiography recording, patients in both the experimental and control groups who met the inclusion criteria completed the Personal Information Form, the Hospital Anxiety Scale, and the Distress Thermometer. Vital signs were recorded using the Vital Signs Monitoring Form.

For patients in the experimental group, selected music was played via a wireless Bluetooth speaker throughout the angiography procedure after admission to the angiography unit and completion of standard preparations. Patients were informed that they could control the volume of the music, including increasing or decreasing the sound level, stopping the music, or restarting it if desired. Patients in the control group underwent the procedure according to the hospital's routine clinical workflow without any music intervention.

During the intraoperative period, anxiety levels of patients in both groups were assessed using the Distress Thermometer, and vital signs were recorded. Fifteen minutes after completion of the procedure, posttest assessments were performed by re-administering the Hospital Anxiety Scale and the Distress Thermometer, and vital signs were recorded again.

Inclusion Criteria:

• Patients aged between 18 and 65 years
• Literate patients
• Patients who voluntarily agree to participate in the study

Exclusion Criteria:

• Clinically unstable patients
• Patients scheduled for emergency angiography
• Patients with hearing impairment
• Patients who have used any analgesic medication prior to the procedure
• Patients unable to communicate in Turkish
• Patients using anxiolytic or sedative medications
• Patients without a psychiatric diagnosis

IPD will not be shared to protect participant privacy and confidentiality.

No parties are masked in this study. Both the participants and the investigators are aware of the intervention. The study is conducted as an open-label trial.