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This study aims to develop an automated instant message-delivered intervention (i.e., EMI) for people with mild cognitive impairment to reduce their NPS, and to investigate the feasibility and effectiveness of the intervention.
Message contents:
The message content library will consist of four parts: 1.orientation, 2. brief mild cognitive impairment education messages, 3. acceptance and commitment therapy messages, 4.booster message.
Message delivery
Control Group:
The control group will receive instant messages about mental health management from GovHK website (https://www.gov.hk/en/residents/health/mental/), which is open to the public.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention group | Experimental | Participants in intervention group will receive the EMI for 9 weeks. Based on the steps of mobile message development recommended by Abroms, et al., our multidisciplinary team - including a neurologist, nurses, clinical psychologists and gerontologists - will develop an ACT message content library and protocol for IM delivery (i.e. EMI). |
|
| Control group | Active Comparator | The control group will receive instant messages about general mental health management from the HKSAR Government website in 9 weeks, which is open to the public (https://www.shallwetalk.hk/en/mental-well-being/mental-well-being-is-related-to-you/), with reminder text messages of follow-up surveys. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| automated instant message-guided neuropsychiatric symptoms management | Behavioral | Participants in intervention group will receive the EMI for 9 weeks. Based on the steps of mobile message development recommended by Abroms, et al., we will develop a message content library and protocol for EMI delivery. |
| Measure | Description | Time Frame |
|---|---|---|
| MBI-C scores | The primary outcome will be MBI-C scores to assess NPSs. A higher MBI-C scores will indicate a higher level of neuropsychiatric symptoms. | at baseline, 10th week and 24th week |
| Measure | Description | Time Frame |
|---|---|---|
| Depressive symptoms (PHQ-9) | Each item was scored on a 4-point scale (0 "not at all" to 3 "nearly every day"). The total score is calculated by summing up the score of all items (range 0-27). High scores indicate worse depressive symptoms. | at baseline, 10th week and 24th week |
| Anxiety symptoms (GAD-7) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Doris Sau Fung Yu, Professor | Contact | +852 3917 6319 | dyu1@hku.hk |
| Name | Affiliation | Role |
|---|---|---|
| Doris Sau Fung Yu, Professor | School of nursing, The University of Hong Kong | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Hong Kong | Recruiting | Hong Kong | Hong Kong |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31713252 | Result | Younas A, Pedersen M, Durante A. Characteristics of joint displays illustrating data integration in mixed-methods nursing studies. J Adv Nurs. 2020 Feb;76(2):676-686. doi: 10.1111/jan.14264. Epub 2019 Nov 25. | |
| 26690917 | Result | Abroms LC, Whittaker R, Free C, Mendel Van Alstyne J, Schindler-Ruwisch JM. Developing and Pretesting a Text Messaging Program for Health Behavior Change: Recommended Steps. JMIR Mhealth Uhealth. 2015 Dec 21;3(4):e107. doi: 10.2196/mhealth.4917. |
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|
| general mental health management | Behavioral | Participants in control group will receive the messages for 9 weeks. The control group will receive instant messages about general mental health management from the HKSAR Government website, which is open to the public (https://www.shallwetalk.hk/en/mental-well-being/mental-well-being-is-related-to-you/), with reminder text messages of follow-up surveys. |
|
A 7-item scale with score ranging from 0 to 21, higher scores indicate higher severity of anxiety symptom |
| at baseline, 10th week and 24th week |
| Quality of life (EuroQol 5-dimension 5-level questionnaire [EQ-5D-5L]) | The EQ-5D-5L assesses five health dimensions: mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, each rated on five levels of severity, with scores ranging from -0.864 to 1, where higher scores indicate better quality of life. Additionally, it includes a visual analogue scale (VAS), ranging from 0 (the worst health imaginable) to 100 (the best health imaginable). | at baseline, 10th week and 24th week |
| Cognitive functions (HK-MoCA) | The total score is calculated by summing up the score of all items. Higher scores indicate better cognitive function. | at baseline, 10th week and 24th week |
| Acceptance of negative emotions and valued-based actions (AAQ-II) | AAQ-II is a measure of psychological flexibility. Each item is rated on a 7-point scale from 1 = never true to 7 = always true. Scores range from 1-49. A lower score indicates a lower level of psychological flexibility. | at baseline, 10th week and 24th week |
| Subjective Cognitive Decline scale (SCD-9) | SCD-9 is a scale detecting subjective cognitive function. Higher socre indicate worse subjective cognitive function. | at baseline, 10th week and 24th week |
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| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
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