A multicenter, retrospective, observational cohort study on intravenous thrombolysis beyond the time window for acute ischemic stroke

1. Patients with acute ischemic stroke, regardless of gender;
2. Age ≥ 18 years old;
3. Time from onset to treatment within 4.5 - 24 hours (the onset time refers to the last time when they appeared normal);
4. Complete relevant clinical data (including gender, age, mRS, NIHSS, etc.).

According to the survey, each center has at least 100 cases of thrombolysis with alteplase or tenecteplase for Acute Ischemic Stroke at 4.5 to 24 Hours each year. Data will be collected for 5 years, and it is estimated that a total of no less than 2,000 cases will be included.