This randomized, stratified, double-blind, two-cell parallel clinical study evaluated the dental plaque prevention efficacy of a stannous fluoride toothpaste compared to a sodium fluoride control toothpaste following a professional dental prophylaxis. Adult subjects brushed twice daily for 14 days with their assigned dentifrice. Plaque was assessed using the Lobene-Soparkar modification of the Turesky Modification of the Quigley-Hein Plaque Index at baseline, Day 1, and Day 14 following periods of oral hygiene abstention.

This two-week, randomized, double-blind, parallel-group study evaluated plaque prevention following dental cleaning. Subjects meeting plaque qualification criteria underwent a complete prophylaxis and were randomized to either a stannous fluoride test dentifrice or a sodium fluoride control dentifrice. Subjects brushed twice daily for two minutes with the assigned product. Plaque accumulation was assessed at baseline, after one day of use, and after 14 days of use following overnight abstention from oral hygiene. Plaque was disclosed and scored on facial and lingual tooth surfaces using the Lobene-Soparkar modified Turesky Plaque Index. Treatment comparisons were performed using ANCOVA with baseline plaque as a covariate.

Inclusion Criteria:

• Good general health based on medical history
• Minimum of 18 natural teeth with scorable surfaces
• Baseline mean plaque score ≥2.0
• Willing to refrain from non-study oral hygiene products
• Willing to abstain from oral hygiene prior to study visits
• Able and willing to comply with study procedures

Exclusion Criteria:

• Known allergy to oral care products
• Conditions limiting normal brushing
• Significant medical conditions affecting study participation
• Pregnant or nursing females
• Severe periodontal disease
• Recent dental prophylaxis
• Recent participation in another dental study

The sponsor does not plan to share individual participant data. Summary results will be provided as required, but no de-identified datasets will be made publicly available.