Mindfulness and meditation based relapse prevention has been proposed as an adjunctive approach for individuals with substance use disorders (SUDs). This completed pilot observational case series describes outcomes from three de-identified participants who completed an eight-week mindfulness and meditation program designed to reduce stress, enhance coping skills, and support sustained recovery.

Participants demonstrated improvements in perceived stress and mindfulness following the intervention. Two participants experienced relapse within 10-12 months, while one participant maintained long-term sobriety. This small case series provides descriptive clinical insights and supports the feasibility of mindfulness-based interventions in real-world treatment settings.

This pilot observational case series evaluated an eight-week mindfulness and meditation-based relapse prevention program delivered to three de-identified adults with substance use disorders. The intervention included weekly guided mindfulness sessions, daily home practice, and group discussions focused on awareness of cravings, emotional regulation, and relapse prevention strategies.

Outcomes were assessed using self-reported perceived stress and mindfulness measures, along with qualitative clinical interviews and participant journals to monitor relapse behavior. All participants demonstrated improvements in perceived stress and mindfulness. Relapse occurred in two participants within one year, while one participant maintained long-term sobriety.

This study was exploratory and descriptive in nature, with a small sample size. Ethics review was not required as all participants were de-identified and the study was conducted as a clinical case series. Findings are intended to inform future research and larger-scale studies of mindfulness-based relapse prevention interventions.

Inclusion Criteria:

• Adults aged 18 years or older
• History of substance use disorder (any substance)
• Enrolled in or referred to an eight-week mindfulness and meditation-based relapse prevention program
• Willing and able to participate in weekly guided sessions, daily home practice, and group discussions
• Able to provide self-reported information on stress, mindfulness, and relapse experiences

Exclusion Criteria:

• Individuals under 18 years of age
• Inability or unwillingness to participate in mindfulness or meditation exercises
• Severe cognitive impairment or psychiatric condition preventing participation in group or home practice
• Participation in concurrent structured relapse prevention programs outside of this study

The study population consisted of three de-identified adults with a history of substance use disorders who participated in an eight-week mindfulness and meditation based relapse prevention program. Participants included two females and one male, ranging in age from 30 to 51 years. All participants engaged in weekly guided sessions, daily home practice, and group discussions. The population was selected from individuals already enrolled in the program and willing to participate in data collection for observational purposes. No restrictions were placed on sex beyond adult eligibility, and participants had varying substance use histories and prior treatment experiences.

Individual participant data (IPD) from this study, including de-identified perceived stress scores, mindfulness scores, and relapse observations, will be made available upon reasonable request to qualified researchers. All data will be fully de-identified to protect participant privacy. Data requests should include a research proposal and data use agreement. The data will be available for three years following publication of the study results. The study dataset is small (three participants) and observational in nature; requests will be reviewed to ensure ethical use and protection of participant confidentiality.

The individual participant data (IPD) and supporting documents will be available starting from the date the study record becomes publicly accessible on ClinicalTrials.gov and will remain available for three years following publication.

IPD will be accessible to qualified researchers who submit a request with a research proposal and agree to a data use agreement. Available materials include de-identified participant data (stress scores, mindfulness scores, relapse observations), the study protocol, and the clinical study report. Data access will be granted following review to ensure ethical use and confidentiality protection.