Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Standardization According to GINA 2025 Recommendations for the Treatment, Management, and Follow-up of Acute Asthma Attacks: Observational, Multicenter Cohort Study.
Patients aged 6 to 17 years presenting to the emergency department with an acute asthma exacerbation were included. Clinical outcomes were compared between a pre-intervention period (October 2024-May 2025) and a post-intervention period (October 2025-May 2026).
Between the two study periods, a structured educational intervention targeting medical and nursing staff was implemented. The intervention consisted of didactic lectures, clinical simulation sessions, case-based discussions, and the dissemination of updated diagnostic and therapeutic flowcharts based on the 2025 Global Initiative for Asthma (GINA) guidelines.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pre-intervention cohort | Pediatric patients aged 6-17 years presenting to the emergency department with an acute asthma exacerbation during the pre-intervention period (October 2024-May 2025). Patients received standard care according to local clinical practice prior to the implementation of the structured educational intervention. Intervention: No intervention (standard of care) | ||
| Post-intervention cohort | Pediatric patients aged 6-17 years presenting to the emergency department with an acute asthma exacerbation during the post-intervention period (October 2025-May 2026), after the implementation of a structured educational intervention for emergency department staff. Intervention: Educational intervention (health care provider-directed) |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Change in the number of correctly reported diagnoses before and after intervention | Assessment of adherence to guideline-based diagnostic and therapeutic management of pediatric patients presenting with acute asthma exacerbations in the emergency department. | Pre-intervention and through study completion, an average of 9 months |
| Percentage of patients with correct timing, dosage, and method of drug administration before and after intervention | Pre-intervention and through study completion, an average of 9 months | |
| Percentage of patients with correct follow-up at discharge | Pre-intervention and through study completion, an average of 9 months | |
| Percentage of patients in whom additional drugs are used in refractory cases | Pre-intervention and through study completion, an average of 9 months | |
| Percentage of patients with correct therapy at discharge | Pre-intervention and through study completion, an average of 9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of acute asthma exacerbations | Number of emergency department visits for acute asthma exacerbations among pediatric patients during the pre- and post-intervention periods. | Pre-intervention and through study completion, an average of 9 months |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
The study population consists of pediatric patients aged 6 to 17 years presenting to the emergency departments of two Italian tertiary-care hospitals (AOU IRCCS Meyer Children's Hospital in Florence and Arcispedale S. Anna in Ferrara) with an acute asthma exacerbation.
Eligible patients were identified through retrospective review of electronic medical records of all emergency department visits occurring during the predefined study periods. Patients were included if they received a discharge diagnosis consistent with acute asthma exacerbation or related conditions (e.g., bronchospasm, asthma attack, asthmatic bronchitis, wheezing).
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Grazia Fenu | Contact | +390555662388 | +390555662388 | grazia.fenu@meyer.it |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Arcispedale S. Anna | Recruiting | Ferrara | FE | 44124 | Italy |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Meyer Children's Hospital IRCCS, Firenze | Recruiting | Florence | 50134 | Italy |