Hyaluronic Acid and Amino Acid Combination Versus Exercise for Chronic Lateral Epicondylitis

A New Era in the Treatment of Chronic Lateral Epicondylitis: Comparison of Targeted Biological Support Using a Hyaluronic Acid and Amino Acid Combination Versus Exercise Therapy: A Retrospective, Controlled Clinical Study

This retrospective, controlled clinical study aims to evaluate the effectiveness of a targeted biological support injection containing a hyaluronic acid and amino acid combination in patients with chronic lateral epicondylitis (tennis elbow). Medical records will be reviewed to compare outcomes between patients treated in routine clinical practice with a 3-dose injection regimen (weeks 0, 2, and 4) plus a home exercise program and those treated with a home exercise program alone. Key outcome measures include pain intensity (VAS), functional status (PRTEE), grip strength, and pressure pain threshold.

Inclusion Criteria:

• Patients aged between 18 and 70 years.
• Patients diagnosed with Lateral Epicondylitis (LE).
• Presence of symptoms persisting for 6 weeks or longer.
• Patients who were treated with either a 3-dose protocol of Hyaluronic Acid + Amino Acid injection combined with a home exercise program, or a home exercise program alone.

Exclusion Criteria:

• History of rheumatic disease.
• History of malignancy.
• Presence of radiculopathy or neuropathy.
• Presence of peripheral circulatory disorders.
• Congenital or acquired upper extremity deformities.
• History of coagulopathy or current use of warfarin therapy.
• Presence of prosthesis, metal implant, or internal fixator in the elbow region.