Placebo-controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus

Multicenter, Randomized, Double-Masked, Placebo-Controlled Study to Evaluate the Safety and Efficacy of GLK-221 Ophthalmic Solution in Subjects With Keratoconus

Multi-center, parallel-group, placebo-controlled trial designed to assess the safety and efficacy of twice-daily topically administered GLK-221 Ophthalmic Solution in subjects with keratoconus.

Inclusion Criteria:

• Be ≥ 18 and ≤ 55 years of age
• Diagnosis of keratoconus in the study eye

Exclusion Criteria:

• Pregnant, lactating or planning a pregnancy
• Currently enrolled, or within 30 days prior to Screening were enrolled, in another investigational drug or device trial