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To evaluate the efficacy of a stannous fluoride toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Test 1 | Experimental | instructed to brush w/ full ribbon, 2x day / 2mins with toothpaste and battery toothbrush provided instructed to 2x day / Swish 20mL for 30 secs with mouthwash provided |
|
| Test 2 | Experimental | instructed to brush w/ full ribbon, 2x day / 2mins with toothpaste and battery toothbrush provided instructed to 2x day / Swish 10mL for 1min with mouthwash provided |
|
| Test 3 | Active Comparator | instructed to brush w/ full ribbon, 2x day / 2mins with toothpaste and manual toothbrush provided instructed to 2x day / Swish 10mL for 1min with mouthwash provided |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 0.454%Stannous fluoride toothpaste | Drug | toothpaste |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Loe-Silness Gingival Index | score from 0 to 3 will be assigned by the examining dentist to all scoreable surfaces | Baseline, 6-weeks, and 12-weeks |
| Rustogi Modification of the Navy Plaque Index | a red disclosing solution will be used to make plaque visible and improve scoring accuracy. Subjects will be instructed to swish approximately 10 drops of the solution in their mouth for 10-15 seconds before expectorating. | Baseline, 6-weeks, and 12-weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Consumer Research Consulting, LLC | Melbourne | Florida | 32935 | United States |
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| 0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe |
| Drug |
mouthwash |
|
| 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste | Drug | toothpaste |
|
| 0.022% Sodium Fluoride mouthwash | Drug | mouthwash |
|
| ID | Term |
|---|---|
| D058225 | Plaque, Amyloid |
| D005891 | Gingivitis |
| ID | Term |
|---|---|
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D007239 | Infections |
| D005882 | Gingival Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D002594 | Cetylpyridinium |
| C015101 | cytidylyl-(3'-5')-cytidine |
| C012980 | fluorophosphate |
| C111976 | Supersmile |
| D014100 | Toothpastes |
| ID | Term |
|---|---|
| D011726 | Pyridinium Compounds |
| D011725 | Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D003802 | Dentifrices |
| D001697 | Biomedical and Dental Materials |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |
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