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| ID | Type | Description | Link |
|---|---|---|---|
| E-31679287-663.05-523405 | Other Identifier | Ethics Committee of Dicle University |
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This randomized controlled trial aims to examine the effects of a weightlifting-based training program on hormonal, metabolic, and lipid profile parameters in athletes. Participants will be randomly assigned to either a weightlifting-based training group or a control group. The training program will be implemented for a specific period, and relevant blood parameters will be evaluated before and after the intervention. The findings of this study may contribute to a better understanding of the physiological effects of weightlifting-based training on athletes.
This study is designed as a randomized controlled trial to investigate the effects of a structured weightlifting training program on hormonal, metabolic, and lipid profile parameters in athletes. Eligible participants will be randomly assigned to either an intervention group undergoing a weightlifting-based training protocol or a control group continuing their usual training routines.
The intervention will be implemented over a predetermined training period, and outcome measures will include selected hormonal, metabolic, and lipid profile markers obtained from blood samples. Measurements will be taken at baseline and at the end of the training period. The results of this study are expected to provide evidence on physiological adaptations associated with weightlifting-based training and offer practical implications for training program design in athletic populations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Powerlifting-Based Training Group | Experimental | Participants performed a structured powerlifting-based training program in addition to their regular basketball training. The intervention was conducted three days per week for six weeks. Each session lasted approximately 60 minutes and included a standardized warm-up, a powerlifting-focused main training phase, and a cool-down period. The training program emphasized the squat, bench press, and deadlift exercises performed with progressive intensity. Accessory exercises targeting lower-body strength, upper-body musculature, and core stability were included. High-intensity bodyweight exercises were also performed to enhance anaerobic capacity and neuromuscular performance. All training sessions were supervised by qualified staff. |
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| Control Group | Other | Participants continued their usual basketball training routines throughout the study period without any additional strength or powerlifting-based exercises. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Powerlifting-Based Training | Other | Participants will perform a structured powerlifting-based training program including squat, bench press, and deadlift exercises, conducted 3 sessions per week for 8 weeks under supervision. |
| Measure | Description | Time Frame |
|---|---|---|
| Mean Change in Fasting Serum Total Testosterone Concentration Measured by ELISA (ng/dL) | Mean difference between baseline and post-intervention fasting serum total testosterone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA). | Baseline and post-intervention (8 weeks) |
| Mean Change in Fasting Serum Cortisol Concentration Measured by ELISA (µg/dL) | Mean difference between baseline and post-intervention fasting serum cortisol concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA). | Baseline and post-intervention (8 weeks) |
| Mean Change in Fasting Serum Growth Hormone Concentration Measured by ELISA (ng/mL) | Mean difference between baseline and post-intervention fasting serum growth hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA). | Baseline and post-intervention (8 weeks) |
| Mean Change in Fasting Serum Thyroid-Stimulating Hormone Concentration Measured by ELISA (µIU/mL) | Mean difference between baseline and post-intervention fasting serum thyroid-stimulating hormone concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA). | Baseline and post-intervention (8 weeks) |
| Mean Change in Fasting Serum Triiodothyronine Concentration Measured by ELISA (ng/dL) | Mean difference between baseline and post-intervention fasting serum triiodothyronine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA). | Baseline and post-intervention (8 weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| Mean Change in Fasting Serum Insulin Concentration Measured by ELISA (µIU/mL) | Mean difference between baseline and post-intervention fasting serum insulin concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA). | Baseline and post-intervention (8 weeks) |
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Inclusion Criteria:
Exclusion Criteria:
Only male athletes were eligible to participate in this study.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Sport Sciences | Tunceli | Center | 62000 | Turkey (Türkiye) | ||
| Munzur University |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42387653 | Derived | Tizar E, Erdogan R. Short-term effects of powerlifting-based training on hormonal, metabolic, and lipid profile markers in male basketball players: a randomized controlled trial. BMC Sports Sci Med Rehabil. 2026 Jul 1. doi: 10.1186/s13102-026-01832-4. Online ahead of print. |
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Individual participant data will not be shared due to ethical restrictions, participant confidentiality concerns, and the absence of participant consent for data sharing beyond the scope of this study.
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Sep 9, 2025 | Feb 4, 2026 | Prot_000.pdf |
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| ID | Term |
|---|---|
| D001800 | Blood Specimen Collection |
| ID | Term |
|---|---|
| D013048 | Specimen Handling |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| Usual Basketball Training | Other | Participants continued their usual basketball training routines without any additional strength or powerlifting-based exercises. |
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| Blood Sampling and Laboratory Analysis | Other | Venous blood samples were collected from participants at baseline and post-intervention following an overnight fast. Hormonal parameters were analyzed using ELISA methods, and metabolic and lipid profile parameters were analyzed using an automated biochemical analyzer. |
|
| Mean Change in Fasting Serum Thyroxine Concentration Measured by ELISA (µg/dL) | Mean difference between baseline and post-intervention fasting serum thyroxine concentrations, measured from venous blood samples using a commercially available enzyme-linked immunosorbent assay (ELISA). | Baseline and post-intervention (8 weeks) |
| Mean Change in Fasting Blood Glucose Concentration Measured by Automated Biochemical Analyzer (mg/dL) |
Mean difference between baseline and post-intervention fasting blood glucose concentrations, measured from venous blood samples using an automated biochemical analyzer. |
| Baseline and post-intervention (8 weeks) |
| Mean Change in Total Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL) | Mean difference between baseline and post-intervention total cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer. | Baseline and post-intervention (8 weeks) |
| Mean Change in Low-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL) | Mean difference between baseline and post-intervention low-density lipoprotein cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer. | Baseline and post-intervention (8 weeks) |
| Mean Change in High-Density Lipoprotein Cholesterol Concentration Measured by Automated Biochemical Analyzer (mg/dL) | Mean difference between baseline and post-intervention high-density lipoprotein cholesterol concentrations, measured from venous blood samples using an automated biochemical analyzer. | Baseline and post-intervention (8 weeks) |
| Mean Change in Triglyceride Concentration Measured by Automated Biochemical Analyzer (mg/dL) | Mean difference between baseline and post-intervention triglyceride concentrations, measured from venous blood samples using an automated biochemical analyzer. | Baseline and post-intervention (8 weeks) |
| Bitlis |
| Tunceli |
| 62000 |
| Turkey (Türkiye) |
| D011677 | Punctures |
| D013514 | Surgical Procedures, Operative |
| D008919 | Investigative Techniques |