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It is a well established fact that the pain of labour can be excrutiating and ways to shorten the duration of labour has been sought after. this study compares the role of intramuscular tramadol and intravenous paracetamol in shortening the duration of labour
Background: The excruciating pain associated with labour as led to different studies aimed at finding pharmacolologic and non pharmacologic ways of shortening the duration of labour. Most agents used are either expensive or associated with fetomaternal adverse effects. This has led to the study of paracetamol and tramadol that have analgesic properties and have shown to have effect on labour duration.
Aim: To compare intravenous paracetamol versus intramuscular tramadol in shortening the duration of labour at Alex Ekwueme Federal University Teaching Hospital and St Patrick's Mile 4 Hospital, Abakaliki, Ebonyi State.
Methodology: It is an open label, non inferiority randomized controlled trial that was conducted on one hundred and eighty-nine parturients in active labour. Group A received 1000mg of intravenous paracetamol while Group B received 100mg of intramuscular tramadol and allocation was in the ratio of 1:1. Labour duration in the active phase was noted. Data were analyzed using SPSS version 25.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| intramuscular tramadol | Active Comparator | 100mg of tramadol was given intramuscularly in active phase of labour |
|
| paracetamol | Experimental | 1000mg of paracetamol given intravenously in active phase of labour |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| paracetamol | Drug | 1000 mg of paracetamol was administered intravenously to participants in active phase of labour |
|
| Measure | Description | Time Frame |
|---|---|---|
| Mean duration of first, second and third stage of labour | the mean of the different stages of labour as well as the total duration of labour | 12 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Assumpta N Nweke | ST Patrick Mission Hospital, Mile $ Abakaliki, Ebonyi State | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assumpta Nnenna Nweke | Abakaliki | Ebonyi State | 480 | Nigeria |
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| ID | Term |
|---|---|
| D000082 | Acetaminophen |
| D014147 | Tramadol |
| ID | Term |
|---|---|
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 |
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| Tramadol hydrochloride | Drug | 100mg of tramadol given in active phase of labour |
|
|
| Aniline Compounds |
| D000588 | Amines |
| D003511 | Cyclohexanols |
| D000441 | Hexanols |
| D005233 | Fatty Alcohols |
| D000438 | Alcohols |
| D004123 | Dimethylamines |
| D008744 | Methylamines |
| D008055 | Lipids |