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| Name | Class |
|---|---|
| GEFA | UNKNOWN |
| CRI | UNKNOWN |
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The purpose of the study is to recruit as many patients as possible presenting with sacroiliitis or authentic axial spondylarthritis and giant cell arteritis. The investigators will also be interested in the association of spondylarthritis and polymyalgia rheumatica given the continuum between these two pathologies. The aim is to investigate whether there is an association between giant cell arteritis and spondylarthritis or polymyalgia rheumatica and spondylarthritis.
Large vessel vasculitis primarily includes Takayasu's arteritis and Giant Cell Arteritis (GCA). The literature describes associations between spondyloarthritis and large vessel vasculitis, particularly with Takayasu's arteritis. Case reports have highlighted specific features in patients presenting with both conditions, such as an older age at spondyloarthritis diagnosis and higher C-reactive protein (CRP) levels, for example.
However, to date, no cases of axial spondyloarthritis associated with confirmed GCA have been reported in the literature.
The investigators plan to recruit cases (patients with GCA and/or polymyalgia rheumatica [PMR] plus spondyloarthritis) and controls (patients with GCA or PMR alone). The investigators will then analyze their characteristics to investigate a potential association between these diseases.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with GCA, spondylarthritis and/or polymyalgia rheumatica | Patients with GCA, spondylarthritis and/or polymyalgia rheumatica |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Description of population | Other | Description of population in the aim of identify demographic or phenotypic factors different between experimental and control populations. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Description of the population of patients with spondylarthritis associated with giant cell arteritis (GCA) or polymyalgia rheumatica (PMR) versus patients with GCA or PMR alone | Identification of demographic or phenotypic factors different between experimental and control populations. | At baseline |
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Inclusion Criteria:
Exclusion Criteria:
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- Experimental group: Adult patient with spondylitis associated with GCA or PMR Control group: Adult patient with GCA or PMR
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mathilde WLODARCZYK | Contact | 0033130754650 | mathilde.wlodarczyk@ght-novo.fr |
| Name | Affiliation | Role |
|---|---|---|
| Omar AL TABAA | Hôpital NOVO | Principal Investigator |
| Auriane CHADELAT | Hôpital NOVO | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CRI (Rheumatism and Inflammatory Club) | Paris | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 1807815 | Background | Healey LA. Relation of giant cell arteritis to polymyalgia rheumatica. Baillieres Clin Rheumatol. 1991 Dec;5(3):371-8. doi: 10.1016/s0950-3579(05)80059-7. | |
| 29450875 | Background | Aydeniz A, Akaltun MS, Gur A, Gursoy S. [Coexistence of polymyalgia rheumatica with ankylosing spondylitis: A case report]. Agri. 2018 Jan;30(1):35-37. doi: 10.5505/agri.2016.69672. Turkish. |
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| ID | Term |
|---|---|
| D013700 | Giant Cell Arteritis |
| D025241 | Spondylarthritis |
| D011111 | Polymyalgia Rheumatica |
| ID | Term |
|---|---|
| D020293 | Vasculitis, Central Nervous System |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D002561 | Cerebrovascular Disorders |
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| GEFA (French Group for the study of large vessel Arteritis) | Toulouse | France |
|
| 25686529 | Background | Corli J, Lemeunier L, Le Gouellec N, Flipo RM. Giant cell arteritis occurring during psoriatic arthritis treated by adalimumab. Joint Bone Spine. 2015 Jul;82(4):291-2. doi: 10.1016/j.jbspin.2014.11.003. Epub 2015 Feb 14. No abstract available. |
| 2716001 | Background | Clementz GL, Gold F, Khaiser N, Zolin WD, Jalovec L. Giant cell arteritis associated with pericarditis and pancreatic insufficiency in a patient with psoriatic arthritis. J Rheumatol. 1989 Jan;16(1):128-9. |
| 27131857 | Background | Garcia-Cezon de la Cruz MDP, Almodovar R, Garcia Perez J, Dhimes PF, Zarco P. Aortitis due to giant cell arteritis and psoriatic arthritis: An uncommon association. Reumatol Clin. 2017 Jul-Aug;13(4):230-232. doi: 10.1016/j.reuma.2016.03.016. Epub 2016 May 4. English, Spanish. |
| 9272303 | Background | Elkayam O, Paran D, Yaron M, Caspi D. Polymyalgia rheumatica in patients with ankylosing spondylitis: a report of 5 cases. Clin Exp Rheumatol. 1997 Jul-Aug;15(4):411-4. |
| 33843285 | Background | Eshed I, Druyan A, Stern M, Bordavka M, Lidar M. The prevalence of sacroiliitis on abdominal MRI examinations of patients with Takayasu arteritis. Acta Radiol. 2022 Mar;63(3):387-392. doi: 10.1177/0284185121996270. Epub 2021 Apr 11. |
| 28718336 | Background | Mielnik P, Hjelle AM, Nordeide JL. Coexistence of Takayasu's arteritis and ankylosing spondylitis may not be accidental - Is there a need for a new subgroup in the spondyloarthritis family? Mod Rheumatol. 2018 Mar;28(2):313-318. doi: 10.1080/14397595.2017.1341592. Epub 2017 Jul 18. |
| 38563865 | Background | Abacar K, Kaymaz-Tahra S, Bayindir O, Ince B, Kutu ME, Yazici A, Ediboglu ED, Demirci-Yildirim T, Ademoglu Z, Omma A, Yasar-Bilge NS, Kimyon G, Kasifoglu T, Emmungil H, Onen F, Akar S, Cefle A, Alpay-Kanitez N, Celik S, Inanc M, Aksu K, Keser G, Direskeneli H, Alibaz-Oner F. Frequency and the effects of spondyloarthritis-spectrum disorders on the clinical course and management of Takayasu arteritis: an observational retrospective study. Clin Rheumatol. 2024 May;43(5):1571-1578. doi: 10.1007/s10067-024-06939-y. Epub 2024 Apr 2. |
| 28412700 | Background | Riviere E, Arnaud L, Ebbo M, Allanore Y, Claudepierre P, Dernis E, Ziza JM, Miceli-Richard C, Philippe P, Richez C, Soubrier M, Belkhir R, Seror R, Mariette X, Pavy S; Club Rhumatismes et Inflammations. Takayasu Arteritis and Spondyloarthritis: Coincidence or Association? A Study of 14 Cases. J Rheumatol. 2017 Jul;44(7):1011-1017. doi: 10.3899/jrheum.160762. Epub 2017 Apr 15. |
| 24310108 | Background | Gan FY, Fei YY, Li MT, Wang Q, Xu D, Hou Y, Zeng XF, Zhang FC. The characteristics of patients having ankylosing spondylitis associated with Takayasu's arteritis. Clin Rheumatol. 2014 Mar;33(3):355-8. doi: 10.1007/s10067-013-2444-7. Epub 2013 Dec 6. |
| 30735804 | Background | Guzel Esen S, Armagan B, Atas N, Ucar M, Varan O, Erden A, Babaoglu H, Sari A, Karadag O, Haznedaroglu S, Ozturk MA, Akdogan A, Tufan A. Increased incidence of spondyloarthropathies in patients with Takayasu arteritis: a systematic clinical survey. Joint Bone Spine. 2019 Jul;86(4):497-501. doi: 10.1016/j.jbspin.2019.01.020. Epub 2019 Feb 6. |
| 29996949 | Background | Kwon OC, Lee SW, Park YB, Oh JS, Lee SH, Hong S, Lee CK, Yoo B, Kim YG. Extravascular manifestations of Takayasu arteritis: focusing on the features shared with spondyloarthritis. Arthritis Res Ther. 2018 Jul 11;20(1):142. doi: 10.1186/s13075-018-1643-7. |
| 21547038 | Background | Momeni M, Taylor N, Tehrani M. Cardiopulmonary manifestations of ankylosing spondylitis. Int J Rheumatol. 2011;2011:728471. doi: 10.1155/2011/728471. Epub 2011 Apr 12. |
| 27222669 | Background | Ozkan Y. Cardiac Involvement in Ankylosing Spondylitis. J Clin Med Res. 2016 Jun;8(6):427-30. doi: 10.14740/jocmr2488w. Epub 2016 May 25. |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D001167 | Arteritis |
| D014657 | Vasculitis |
| D017445 | Skin Diseases, Vascular |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D013166 | Spondylitis |
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009135 | Muscular Diseases |
| D012216 | Rheumatic Diseases |
| D003240 | Connective Tissue Diseases |