Early Postoperative Pain Following a Limb Amputation

Early Postoperative Pain and Functional Recovery Following a Limb Amputation: a Retrospective Observational Study.

The primary aim of this study is to characterize the trajectory of pain and functional recovery in the first post-operative period following a limb amputation. Secondarily, this study aims to conduct an exploratory analysis to evaluate potential associations between clinical, demographical and therapeutical variables and primary outcomes including pain intensity, pain control and functional recovery.

This retrospective observational study will be conducted at IRCCS Istituto Ortopedico Rizzoli. All patients who underwent an amputation at the IRCCS Istituto Ortopedico Rizzoli between January 1st 2023 and December 31st 2025 will be screened for eligibility based on predefined inclusion criteria. Once a patient is included into the study, all relevant data will be collected from their medical records.

Inclusion Criteria:

• Patients ≥ 18 years of age
• Patients who underwent an amputation to any limb, regardless of location or diagnosis

Exclusion Criteria:

• Patients with severe cognitive impairment or diagnosed with dementia
• Patients deceased or in critical conditions within 48 hours of the intervention
• Previous amputation to any limb
• Admission to the hospital because of a stump revision