This observational study aims to construct and validate the performance of a multimodal predictive model in forecasting the outcomes of neoadjuvant therapy in patients with NSCLC.

The core research question is: Can a multi-model approach predict outcomes of neoadjuvant therapy for non-small cell lung cancer and provide clinical recommendations?

Inclusion Criteria:

1. pathologically diagnosed non-small cell lung cancer
2. The treatment plan is：receiving neoadjuvant chemo-immunotherapy during the study period, followed by surgical resection

Exclusion Criteria:

1. recurrent or metastatic lung cancer;
2. patients with other primary tumors

NSCLC patients suitable for neoadjuvant therapy

Due to patient and hospital ethical requirements, this project does not currently meet the criteria for Individual Patient Data (IPD).