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The purpose of this research is to determine if meniscus root repair with or without centralization will have an impact on postoperative pain, function, activity levels, patient satisfaction, and incidence of revision meniscus surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Repair with meniscus centralization | Experimental | Medial meniscus posterior root tear (MMPRT) surgical repair with meniscus centralization |
|
| Repair without centralization | Active Comparator | Medial meniscus posterior root tear (MMPRT) surgical repair without centralization |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Medial meniscus posterior root tear (MMPRT) repair with meniscus centralization | Procedure | The centralization technique involves placement of 1.8-mm Knotless FiberTak suture anchors along the periphery of the tibial plateau, starting from the posteromedial corner and progressing anteriorly. The anchors are deployed using a curved drill guide, and sutures are passed in a mattress configuration to re-tension the meniscotibial ligament to centralize the meniscus. Once centralization is complete, the posterior root tear is repaired using an anatomic suture anchor for aperture medial meniscus root fixation. |
| Measure | Description | Time Frame |
|---|---|---|
| Meniscus extrusion measurement | Meniscus extrusion is measured in millimeters (mm) on coronal MRI at the level of the tibial spine | Baseline (Preoperatively), 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Kellgren-Lawrence grade on X-ray | The Kellgren-Lawrence (KL) system is a 0-4 scale used to grade the severity of knee osteoarthritis (OA) based on X-ray. It ranges from Grade 0 (no changes) to Grade 4 (severe). | Baseline (Screening), 12 months, 24 months |
| Change in Tegner Activity Score |
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Inclusion Criteria:
Pre-operative Exclusion:
Arthroscopy Inclusion Criteria:
Arthroscopy Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Aaron J. Krych, MD | Mayo Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Steadman Clinic | West Vail | Colorado | 81657 | United States | ||
| Hospital for Special Surgery at Naples Comprehensive Health (HSS at NCH), |
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|
| Medial meniscus posterior root tear (MMPRT) repair without meniscus centralization | Procedure | The posterior root tear is repaired using an anatomic suture anchor for aperture medial meniscus root fixation. |
|
The Tegner Activity Questionnaire is a 1-item questionnaire rating physical activity from 0 (Disabled) to 10 (Elite competitive athlete). Total scores range from 0 - 10, with higher scores indicating a higher level of activity. |
| Baseline, 2 weeks, 6 weeks, 3 months, 6 months, 12 months, 24 months |
| Change in Visual Analog Scale (VAS) Questionnaire score | The VAS is a 2-item questionnaire assessing pain using a scale of 0 (No pain) to 10 (Worst pain). Total scores range from 0 - 10, lower scores indicating lower pain and higher scores indicating greater pain. | Baseline, 2 weeks, 6 weeks, 3 months, 6 months, 12 months, 24 months |
| Change in Knee Injury and Osteoarthritis Outcome Score Jr. (KOOS, JR) Questionnaire score | The KOOS JR is a questionnaire designed to measure outcomes for patients with knee replacements. Questions focus on knee stiffness, pain, and function for daily activities and are assessed on a 5 point Likert-scale between 0 (None) and 4 (Extreme). Total scores range from 0 - 28, with higher scores indicating a greater impact of pain on daily functioning. | Baseline, 2 weeks, 6 weeks, 3 months, 6 months, 12 months, 24 months |
| Change in International Knee Documentation Committee (IKDC) Questionnaire score | The International Knee Documentation Committee (IKDC) Subjective Knee Evaluation assesses overall function over 3 domains: symptoms, athletic activity, and knee function. Higher scores indicate higher levels of function and lower levels of symptoms. | Baseline, 2 weeks, 6 weeks, 3 months, 6 months, 12 months, 24 months |
| Change in Likert Knee Questionnaire score | The Likert Knee Questionnaire is a 1-item survey asking the patient to rate knee pain post-surgery on a Likert scale where 0 (Much better than before surgery) and 5 (Much worse than before surgery). | Baseline, 2 weeks, 6 weeks, 3 months, 6 months, 12 months, 24 months |
| Surgery Satisfaction Questionnaire | The Surgery Satisfaction Questionnaire is a 1-item survey asking the patient to rate satisfaction with knee surgery on a Likert scale where 0 (Not at all) and 10 (Most Satisfied). | 2 weeks, 6 weeks, 3 months, 6 months, 12 months, 24 months |
| Naples |
| Florida |
| 34110 |
| United States |
| Mayo Clinic | Rochester | Minnesota | 55902 | United States |
| ID | Term |
|---|---|
| D014945 | Wound Healing |
| ID | Term |
|---|---|
| D012038 | Regeneration |
| D001686 | Biological Phenomena |
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