Oral Probiotics for Halitosis in Healthy Adults

Efficacy of Oral Probiotics on Cysteine-Induced Halitosis in Healthy Adult Volunteers.

The aim of this study is to evaluate efficacy of a probiotic lozenge containing BLIS M18, BLIS K12 and a prebiotic in healthy adults.

This is a double-blind, randomized controlled colonization pilot study with no crossover to evaluate the efficacy of probiotic lozenges on halitosis in healthy adults.

Participants will be randomly assigned to 2 groups consuming probiotic lozenge containing Streptococcus salivarius M18 and K12 and with prebiotic over a 13 day period. Breath scores will be measured at predetermined time points pre and post intervention.

Inclusion Criteria:

• Participants should be otherwise healthy,
• practice good oral hygiene,
• 18 - 70 years of age

Exclusion Criteria:

• on antibiotic therapy,
• immunocompromised (have a weakened immune system)
• history of autoimmune disease,
• allergy or sensitivity to dairy,
• have an active periodontal disease, any known allergy or sensitivity to components of the test product or cysteine solution.