Virtual Reality-Enhanced Rehabilitation for Cognitive Recovery in Acute Post-Stroke Patients: Pilot Study

Effects of Virtual Reality-Enhanced Rehabilitation on Cognitive Recovery in Acute Post-Stroke Patients: a Pilot Study

Post-stroke rehabilitation is essential for maximising the recovery of cognitive function. Virtual reality (VR) has emerged as a promising adjunct to conventional rehabilitation therapy (CRT), with the potential to enhance cognitive performance outcomes. This study aims to evaluate the effects of VR-based rehabilitation compared with CRT on cognitive function and activities of daily living in patients with acute stroke.

The investigators will conduct a prospective randomised single- blind pilot controlled trial to evaluate the efficacy of VR-based rehabilitation with the Bimeo PRO system on cognitive function and activities of daily living in patients with acute stroke. Participants will be randomly assigned to a two-week VR training program combined with conventional therapy (experimental group) or to conventional therapy alone (control group).

Inclusion Criteria:

• Adults ≥18 years.
• First-ever acute stroke, occurring <7 days before therapy start
• Cognitive impairment on admission (Mini-Mental State Examination score < 24
• Ability to understand and perform virtual reality (VR) tasks.

Exclusion Criteria:

• Severe cognitive impairment that precludes following instructions.
• Aphasia or severe visual/hearing impairment that prevents meaningful participation.
• End-stage/terminal illness.