Melatonin on Post Operative Pain After CS

The Effect of Preoperative Oral Melatonin on Postoperative Pain Control After Cesarean Section: A Dose Comparison Study

The goal of this clinical trial is to learn if melatonin will decrease pain after C.S. The main questions it aims to answer are:

Does melatonin lower the number of times participants need to use a rescue analgesia? What medical problems do participants have when taking melatonin? Researchers will compare different doses of melatonin to see the ideal dose to decrease pain after C.S.

Participants will:

Take melatonin 30 min before C.S and will be observed for 24 hours for pain and consumption of other analgesia

Inclusion Criteria:

• - Women aged 18-40 years.
• Scheduled for elective cesarean section.
• Ability to provide informed consent.

Exclusion Criteria:

• Known hypersensitivity to melatonin or opioids
• Chronic use of analgesics, sedatives, or antidepressants.
• History of sleep disorders or psychiatric illness.
• Complicated pregnancies (e.g., preeclampsia, gestational diabetes).
• Body mass index (BMI) > 35 kg/m².
• Emergency cesarean sections.
• Severe systemic diseases (e.g., liver or kidney dysfunction).