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Evaluation of adherence, persistence, and efficacy of treatment with Bempedoic acid in a real-life Italian population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Subjects with hyperlipidaemia under Bempedoic acid treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bempedoic acid | Drug | film-coated tablets |
|
| Measure | Description | Time Frame |
|---|---|---|
| Description of adherence to treatment with Bempedoic acid in a real-life Italian population | Adherence will be assessed in terms of Medical Possession Ratio (MPR), which is defined as the ratio between the treatment units dispensed during the treatment period and the duration of the treatment period itself. | 6-12-24-36 months |
| Description of efficacy of treatment with Bempedoic acid in a real-life Italian population | Efficacy of treatment will be evaluated as a change in the LDL (deltaLDL) value from the start of treatment (percentage and absolute value). | 6-12-24-36 months |
| Description of persistence to treatment with Bempedoic acid in a real-life Italian population | Persistence will be assessed in terms of therapeutic continuity from the start of treatment to enrollment. | 6-12-24-36 months |
| Measure | Description | Time Frame |
|---|---|---|
| Description of safety of treatment with Bempedoic acid in a real-life Italian population | Safety will be evaluated in terms of adverse reactions or intolerance to the drug. | 6-12-24-36 months |
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Inclusion Criteria:
Exclusion Criteria:
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The study population includes patients from Italy who have received Bempedoic acid as part of routine clinical management of their hyperlipidaemia, based on national reimbursement criteria at the time of enrollment.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Pasquale Perrone Filardi | Contact | +39081/7462224 | fpperron@unina.it |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Federico II University of Naples, Department of Advanced Biomedical Sciences | Recruiting | Naples | Napoli | 80131 | Italy |
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| ID | Term |
|---|---|
| D006937 | Hypercholesterolemia |
| ID | Term |
|---|---|
| D006949 | Hyperlipidemias |
| D050171 | Dyslipidemias |
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |
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| ID | Term |
|---|---|
| C581236 | 8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid |
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| D009750 |
| Nutritional and Metabolic Diseases |