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This study aims to explore the feasibility and scientific validity of carotid-jugular Doppler in evaluating volume tolerance in shock patients (with the VExUS score as an important reference standard), and to conduct an in-depth analysis of the correlation between its monitoring indicators and patient prognosis.The primary endpoint is comparison of the agreement between hands-free carotid-jugular Doppler and the VExUS score in evaluating volume tolerance.The secondary endpoint is correlation between volume tolerance assessed by hands-free carotid-jugular Doppler and the clinical outcomes of shock patients.
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| Measure | Description | Time Frame |
|---|---|---|
| Hands-free Carotid Artery and Vein Doppler Parameters | Elevate the patient's upper body to 45°, keep the legs flat, place the long axis of the probe perpendicular to the carotid vessels (with the probe height not exceeding the upper edge of the thyroid cartilage), locate the optimal signals of the common carotid artery and internal jugular vein waveforms, and then fix the probe. | Time of shock in ICU within 3 days |
| Measure | Description | Time Frame |
|---|---|---|
| PiCCO | Inject cold saline through central venous catheterization, sense temperature changes via arterial catheter, and obtain hemodynamic parameters such as cardiac output by combining thermodilution and pulse contour analysis. | Time of shock in ICU within 3 days |
| Venous Excess Ultrasound Score |
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Inclusion Criteria:
Exclusion Criteria:
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Patients admitted to the ICU
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zhongda Hospital Affiliated to Southeast University | Nanjing | Jiangsu | 210000 | China |
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| ID | Term |
|---|---|
| D012769 | Shock |
| D004487 | Edema |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
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Evaluate the diameter, waveform, etc. of the inferior vena cava, hepatic veins, portal vein, and intrarenal veins sequentially via ultrasound, and comprehensively derive a grade ranging from 0 to 3.Grade 0: No congestion; Grade 1: Mild congestion; Grade 2: Moderate congestion; Grade 3: Severe congestion. |
| Time of shock in ICU within 3 days |
| Bioelectrical Impedance Analysis | Attach electrodes to the patient's limbs, input basic information, measure impedance of multiple parts with multi-frequency technology, and quickly obtain parameters such as body composition. | Time of shock in ICU within 3 days |
| Duration of shock | Time of shock in ICU within 28 days | Time of shock in ICU within 28 days |
| Duration of Mechanical Ventilation | Duration of Mechanical Ventilation During ICU Admission | up to 24 weeks |
| Total Length of Hospital Stay | Total Length of Hospital Stay | up to 24 weeks |
| Length of ICU stay | Length of ICU stay | up to 24 weeks |
| mortality of 28 days | Incidence of death during 28 days | Incidence of death during 28 days |
| In-hospital Mortality | In-hospital Mortality | up to 24 weeks |
| Vasoactive Agent Dosage | Vasoactive Agent Dosage During ICU Admission | up to 24 weeks |
| Time without vasoactive agents within 28 days | Time without vasoactive agents within 28 days | Time without vasoactive agents within 28 days |