Trunk Stability, Balance, and Fatigue in Minimally to Moderately Disabled People With Multiple Sclerosis

The Relationship Between Trunk Stability, Balance, Mobility, Upper Limb Performance, and Fatigue in Minimally to Moderately Disabled People With Multiple Sclerosis

The goal of this observational study is to investigate the relationship between trunk stability and balance, mobility, upper limb performance, and fatigue in people with multiple sclerosis (MS) with minimal to moderate disability levels.

The main questions it aims to answer are:

1. Is trunk stability associated with balance, mobility, upper limb performance, and fatigue in people with multiple sclerosis with minimal to moderate disability?
2. Do balance, mobility, upper limb performance, and fatigue differ between minimally and moderately disabled people with multiple sclerosis?

Participants with a diagnosis of multiple sclerosis and Expanded Disability Status Scale (EDSS) scores ≤2 (minimally disabled) and 2.5-4 (moderately disabled) will be included in the study.

Participants will undergo standardized clinical assessments to evaluate trunk stability, balance, mobility, upper limb performance, and fatigue during a single assessment session. No intervention will be applied as part of the study, and all measurements will reflect participants' current functional status.

Inclusion Criteria:

• The diagnosis of multiple sclerosis was confirmed by a neurologist.
• Expanded Disability Status Scale (EDSS) score between 0 and 4
• Age between 18 and 65 years
• Accepting participation in the study voluntarily

Exclusion Criteria:

• An MS attack within the last three months
• Pregnancy
• Presence of cardiovascular, pulmonary, or orthopedic conditions that would prevent participation in exercise
• A disease that can affect the immune system, such as infection or cancer
• Additional neurological disease