Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Women with polycystic ovarian syndrome (PCOS) may complain dryness of their eyes especially obese ones. lifestye changes are main treatrment fro both problems
Forty females with PCOS, eye dryness , and obesity will asigned to group I or Group II, n=20 for each group. Both groups will receive metformin thrice times daily and low calorie diet for 12 weeks. Group I, additionally will perform one hour of treadmill walking thrice weekly for 12 weeks.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group number 1 | Experimental | twenty females with PCOS, eye dryness , and obesity will receive metformin thrice times daily and low calorie diet for 12 weeks. Group I, additionally will perform one hour of treadmill walking thrice weekly for 12 weeks. |
|
| group number 2 | Active Comparator | Twenty females with PCOS, eye dryness , and obesity will receive metformin thrice times daily and low calorie diet for 12 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| exercise and limiting diet | Behavioral | twenty females with PCOS, eye dryness , and obesity will receive metformin thrice times daily and low calorie diet for 12 weeks. Group I, additionally will perform one hour of treadmill walking thrice weekly for 12 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| schrimer test | it is a test for assessment dye dryness | it will be measured after 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Ocular surface disability index | it is a questionaire for assessment dye dryness | It will be measured after 12 weeks |
| dry eye scoring system | it is a questionaire for assessment dye dryness |
Not provided
Inclusion Criteria:
Exclusion Criteria:
based on self-representation of gender identity.
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ali MA Ismail, lecturer | Contact | 01005154209 | ali.mohamed@pt.cu.edu.eg | |
| Ali Ismail | Contact | 01031321109 | allooka2012@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Ali MA Ismail, lecturer | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University | Recruiting | Giza | Dokki | Egypt |
Not provided
| ID | Term |
|---|---|
| D011085 | Polycystic Ovary Syndrome |
| D015352 | Dry Eye Syndromes |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D010048 | Ovarian Cysts |
| D003560 | Cysts |
| D009369 | Neoplasms |
| D010049 | Ovarian Diseases |
| D000291 |
Not provided
Not provided
| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| diet limitation | Behavioral | twenty females with PCOS, eye dryness , and obesity will receive metformin thrice times daily and low calorie diet for 12 weeks. |
|
| It will be measured after 12 weeks |
| Tear film break-up time | it is a test for assessment dye dryness | It will be measured after 12 weeks |
| body mass index | it will be assessed on empty stomach and bowel | it will be measured after 12 weeks |
| wasit hip ratio | it will be assessed by dividing wasit circuference on hip circumference | It will be measured after 12 weeks |
| wasit circumference | it will be assessed by tape measure | It will be measured after 12 weeks |
| testesterone | it will be assessed in serum | It will be measured after 12 weeks |
| LH:FSH ratio | The LH (Luteinizing Hormone) to FSH (Follicle-Stimulating Hormone) ratio shows the balance between these reproductive hormones | It will be measured after 12 weeks |
| dehydroepiandrosterone | it will ne assessed in serum | It will be measured after 12 weeks |
| Adnexal Diseases |
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D000091662 | Genital Diseases |
| D006058 | Gonadal Disorders |
| D004700 | Endocrine System Diseases |
| D007766 | Lacrimal Apparatus Diseases |
| D005128 | Eye Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |