Comparison Between Two Techniques in Treatment of Female Stress Urinary Incontinence

Comparison Between the Effect of Periurethral Injection of Platelet-rich Plasma VS Platelet Rich Fibrin in Treatment of Female Stress Urinary Incontinence

compare the therapeutic effect of periurethral injection of autologous platelet-rich plasma (PRP) and injectable platelet rich fibrin (i-PRF) in treatment of female stress urinary incontinence and comparing the need for re-injection in the two groups.

Inclusion Criteria:

• Female patients with primary symptoms of SUI confirmed by patient's medical history and clinical examination, including a focused incontinence evaluation

  • Age range of 30-75 years
  • Females unfit for surgery
  • Females with SUI recurrence after previous surgical procedure by suburethal sling
  • Females refusing surgical interventions

Exclusion Criteria:

• Residual urine volume exceeding 100 cc after excretion
• Evidence of detrusor over-activity on the urodynamic test
• Active urinary tract or vaginal infection
• Malignancies of the genitourinary system
• Patients with genitourinary fistula or urethral diverticulum