This study aims to compare the effectiveness and safety of two commonly used antihistamines, bilastine 20 mg and levocetirizine 5 mg, in patients diagnosed with chronic urticaria. Chronic urticaria is a skin condition characterized by recurrent itchy wheals that significantly affect quality of life.

Eligible participants will be randomly assigned to receive either bilastine or levocetirizine for a defined treatment period. The severity of symptoms, improvement in itching and wheals, and any adverse effects will be assessed during follow-up visits.

The results of this study will help determine which treatment provides better symptom control with fewer side effects in patients with chronic urticaria.

Inclusion Criteria:

• Patients with diagnosis of CSU as per operational definitions.
• Patients already taking Bilastine 20 mg and still getting new lesions.
• UAS7 score >3
• Age range of 18-70 years
• Both male and female patients

Exclusion Criteria:

• • women Patients who have already received treatment of CSU other than Bilastine.

  • Patients taking oral or topical corticosteroids
  • Pregnant or lactating
  • Patients with hereditary angioedema, atopic dermatitis, systemic immune disorders, collagen vascular diseases, immunocompromised status, Chronic liver or kidney failures