Pattern of Treatment and Outcomes of Locally Advanced Rec... | NCT07363863

Studies
Pattern of Treatment and Outcomes of Locally Advanced Rectal Carcinoma

NCT07363863

Sponsor

Sohag University

Status

Not yet recruiting

Last Update Posted

Jan 23, 2026Actual

Enrollment

100Estimated

Phase

Not provided

Conditions

Rectal Carcinoma

Interventions

No Intervention (subjects were previously treated with Onglyza®)

Countries

Not provided

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Nov 2025

Overall Recruitment Status or Expanded Access Status

Not yet recruiting

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Mar 1, 2026Estimated

Primary Completion Date

Jul 1, 2026Estimated

Completion Date

Oct 1, 2026Estimated

First Submitted Date

Nov 27, 2025

First Submission Date that Met QC Criteria

Jan 14, 2026

First Posted Date

Jan 23, 2026Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jan 14, 2026

Last Update Posted Date

Jan 23, 2026Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

the study will discuss different pattern of treatment and the outcomes of locally advanced rectal carcinoma as a retrospective study.

The study will be conducted at Department of Clinical Oncology, Sohag University Hospital and Sohag Cancer center, Sohag, Egypt.

including patients diagnosed and treated between 2018 and 2025. and the data will be collected from reports .

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

100Estimated

Arms/Interventions Module

Arm Groups

Not provided

Interventions

Name	Type	Description	Arm Group Labels	Other Names
No Intervention (subjects were previously treated with Onglyza®)	Other	no intervention

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Estimation of overall survival (OS ).		2018 _ 2025
Estimation of Response rate .		2018-2025
Estimation of disease-free survival (DFS) .		2018-2025

Secondary Outcomes

Measure	Description	Time Frame
treatment-related toxicity: (graded by CTCAE v5).		2018-2025

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

patients who were more than18 years old at time of diagnosis.
Patients with histologically confirmed rectal carcinoma.
Stage II-III (locally advanced) disease at initial diagnosis.

Exclusion Criteria:

Patients with distant metastasis at presentation.
Patients diagnosed with double malignancy.
Patients with incomplete medical records.
Organ failure

Accepts Healthy Volunteers

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

90 Years

Standard Ages

AdultOlder Adult

Study Population

The study will be conducted at Department of Clinical Oncology, Sohag University Hospital and Sohag Cancer center, Sohag, Egypt.

Sampling Method

Non-Probability Sample

Condition Browse Module

MeSH Terms

ID	Term
D012004	Rectal Neoplasms

Ancestor Terms

ID	Term
D015179	Colorectal Neoplasms
D007414	Intestinal Neoplasms
D005770	Gastrointestinal Neoplasms
D004067	Digestive System Neoplasms

Browse Leaves

Not provided

Browse Branches

Not provided

Intervention Browse Module

MeSH Terms

ID	Term
C502994	saxagliptin

Ancestor Terms

Not provided

Browse Leaves

Not provided

Browse Branches

Not provided