hronic obstructive pulmonary disease (COPD) is a common lung disease that can worsen suddenly, leading to hospital admission. During these exacerbations, breathing becomes unstable and recovery is difficult to predict. Currently, doctors lack simple tools to monitor how patients recover day by day during hospitalization and after discharge.

This observational study aims to describe how breathing patterns during sleep change over time in patients hospitalized for a COPD exacerbation. Breathing will be monitored using standard sleep recordings and a non-contact sensor placed under the mattress, which measures breathing without disturbing the patient.

By better understanding how nocturnal breathing variability evolves during recovery, this study may help identify early signs of improvement or deterioration, support safer hospital discharge decisions, and improve follow-up after hospitalization for COPD exacerbation

Inclusion Criteria

• Adults (≥ 18 years) with a confirmed diagnosis of chronic obstructive pulmonary disease (COPD) based on spirometry
• Hospitalized for an acute exacerbation of COPD for less than 24 hours at the time of inclusion
• Admitted to an acute medical ward
• Able to provide written informed consent
• Affiliated with the national health insurance system

Exclusion Criteria

• Ongoing invasive or non-invasive mechanical ventilation at the time of inclusion
• Long-term non-invasive ventilation or positive airway pressure therapy prior to hospitalization
• Use of an anti-pressure (anti-decubitus) mattress incompatible with the study devices
• Severe anxiety disorders interfering with study procedures
• Known allergy to materials used for sensor placement
• Pregnancy or breastfeeding
• Minor or legally protected adult (guardianship, curatorship) or deprivation of liberty
• Lack of health insurance coverage

The study population consists of adult patients with a confirmed diagnosis of chronic obstructive pulmonary disease (COPD) who are hospitalized for an acute exacerbation. Eligible participants are included within the first 24 hours of admission to an acute medical ward and are able to provide informed consent.

All participants have COPD diagnosed by spirometry according to standard criteria and are admitted for management of an exacerbation not requiring invasive or non-invasive mechanical ventilation at the time of inclusion. Patients receiving long-term positive airway pressure therapy or home non-invasive ventilation are excluded.

The study population reflects a real-life hospitalized COPD cohort, encompassing a range of disease severity, clinical trajectories, and comorbidities commonly observed during acute exacerbations. Participants are followed during hospitalization and up to six weeks after discharge to characterize changes in nocturnal ventilatory patterns during recovery.