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The goal of this observational retrospective cohort study is to examine the association between mode of delivery and early postpartum depressive symptoms in adult women who delivered at Massachusetts General Hospital. Specifically, the study evaluates whether the urgency of cesarean delivery (elective versus emergency) is associated with differences in Edinburgh Postnatal Depression Scale (EPDS) scores at 6-8 weeks postpartum, compared with elective cesarean delivery and vaginal delivery. The EPDS is a validated 10-item self-report questionnaire with scores ranging from 0 to 30, where higher scores indicate more severe depressive symptoms.
The primary questions are whether EPDS scores differ among women undergoing emergency cesarean delivery, elective cesarean delivery, and vaginal delivery, and whether perioperative and obstetric factors are associated with postpartum depressive symptoms.
This study involves retrospective analysis of de-identified electronic health record data. Participants will not undergo any study-specific interventions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| elective cesarean | patients who undergone elective cesarean | ||
| urgent cesarean | patients undergone urgent cesarean | ||
| vaginal delivery | patients who delivered by vaginal pass |
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| Measure | Description | Time Frame |
|---|---|---|
| Edinburgh Postnatal Depression Scale (EPDS) scores, a 10-item self-reported screening tool for postpartum depression (range: 0-30, with higher scores indicating more severe depressive symptoms) | 6-8 weeks postpartum |
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of postpartum depression | Prevalence of postpartum depression (EPDS ≥ threshold) across delivery groups. | 6-8weeks |
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Inclusion Criteria:
Underwent cesarean delivery (elective or emergency) or vaginal delivery during the study period
Age 18 years or older
Completed at least one Edinburgh Postnatal Depression Scale (EPDS) assessment at 6-8 weeks postpartum
Have complete perioperative data available
Exclusion Criteria:
Missing 6-8 week postpartum EPDS scores
Pregnancy with fetal demise, severe obstetric complications, or atypical maternal conditions
History of severe psychiatric disorders (e.g., schizophrenia, bipolar disorder), when identifiable
Incomplete perioperative medical records
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adult patients (≥18 years old) who underwent cesarean delivery or vaginal delivery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jingping Wang, MD PhD | Contact | 6179369136 | jwang23@mgh.harvard.edu |
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