Effect of Topical Argan Oil on Healing After Laser Depigm... | NCT07357883

Studies
Effect of Topical Argan Oil on Healing After Laser Depigmentation.

NCT07357883

Sponsor

Ghada Adayil

Status

Completed

Last Update Posted

Jan 22, 2026Actual

Enrollment

40Actual

Phase

Not Applicable

Conditions

Gingival Hyperpigmentation
Laser Depigmentation
Topical Argan Oil
Postoperative Gingival Healing

Interventions

Laser Depigmentation

Countries

Egypt

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jan 2026

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Oct 29, 2025Actual

Primary Completion Date

Dec 22, 2025Actual

Completion Date

Jan 10, 2026Actual

First Submitted Date

Jan 14, 2026

First Submission Date that Met QC Criteria

Jan 14, 2026

First Posted Date

Jan 22, 2026Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jan 14, 2026

Last Update Posted Date

Jan 22, 2026Actual

Sponsor/Collaborators Module

Responsible Party, by Official Title

Ghada Adayil, Lecturer - Periodontology Department - Faculty of Dentistry - Cairo University., Cairo UniversitySponsor-Investigator

Lead Sponsor

Ghada AdayilOTHER

Collaborators

Not provided

Oversight Module

Has Data Monitoring Committee (DMC)

Yes

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

Effect of Argan oil vs placebo on healing after laser depigmentation

Detailed Description

Evaluate the effect of Argan oil vs. placebo on post-operative healing after laser depigmentation. as well as Compare pain levels (VAS score), gingival pigmentation recurrence, and patient satisfaction between groups at predetermined follow-up intervals.

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

40Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Topical Argan Oil	Experimental	Applied post-laser depigmentation	Procedure: Laser Depigmentation
Reference placebo	Placebo Comparator	Identical placebo formulation	Procedure: Laser Depigmentation

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Laser Depigmentation	Procedure	Laser protocol: Diode laser, wavelength 810-980 nm, continuous mode, initiated fiber tip 400 µm, power 1.5-2 W.	Reference placebo Topical Argan Oil

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Effect of Argan oil	Evaluate the effect of Argan oil vs. placebo on post-operative Gingival healing	14 days

Secondary Outcomes

Measure	Description	Time Frame
Visual Analog Scale (VAS)	Compare pain levels (VAS score) , gingival pigmentation recurrence, and patient satisfaction between groups.	14 days

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Patients aged 18-40 with moderate/severe physiological gingival pigmentation
Good general and periodontal health.

Exclusion Criteria:

Systemic diseases affecting healing (e.g., uncontrolled diabetes).
Smokers or tobacco chewers.
Pregnant/lactating women.
Previous depigmentation procedures in the last 2 years.

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

40 Years

Standard Ages

Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Faculty of Dentistry, Cairo University		Cairo	Cairo Governorate		Egypt

IPD Sharing Statement Module

Plan to Share IPD

Description

Not provided

Types

Not provided

Time Frame

Not provided

Access Criteria

Not provided

URL

Not provided