This study aims to compare the efficacy of probiotic-based mouthwashes versus ethyl lauroyl arginate-containing mouthwashes in reducing Streptococcus mutans count, dental plaque accumulation, and salivary pH among a group of Egyptian schoolchildren.

Dental caries remains one of the most prevalent chronic infectious diseases among Egyptian schoolchildren, with Streptococcus mutans (S. mutans) playing a primary etiological role due to its acidogenic and aciduric properties, which contribute to enamel demineralization and plaque formation.

Ethyl Lauroyl Arginate (LAE), a cationic surfactant derived from lauric acid and arginine, has demonstrated potent bactericidal activity against cariogenic organisms, including S. mutans, while also reducing biofilm formation and preserving oral microbiome balance.

Inclusion Criteria:

• Healthy Egyptian schoolchildren aged 6-12 years.
• Good general health.
• Mild to moderate dental plaque accumulation.
• Parental/caregiver willingness to provide consent

Exclusion Criteria:

• Antibiotic or antimicrobial use within the last month.
• Allergies to the mouthwash components.
• Systemic diseases affecting oral health.
• Orthodontic appliances or extensive dental restorations.

The data will be available upon a reasonable request from the corresponding author after the end of study for one year.

After the end of study for one year.

The data will be available upon a reasonable request from the corresponding author.