This research aims to investigate the effect of positioning times on the risk of pressure injury in critically ill patients.

Pressure injuries, considered an indicator of quality of care, remain a significant concern today. They are a health problem that reduces the patient's quality of life, complicates the treatment process, and significantly increases costs. Immobility is one of the main risk factors for pressure injury development. In healthy individuals, discomfort occurs in an area subjected to pressure for a long enough period to cause ischemia, and the person changes their position via the afferent sensorimotor feedback system. Fewer than 20 movements per night significantly increase the risk of ulcer development. The factor causing ulcer formation is the inability of the individual to relieve the pressure applied to the tissue. Patients with limited mobility cannot change their body position on their own, and tissue perfusion is impaired in pressure-exposed areas, facilitating ulcer formation. Both the intensity and duration of pressure affect the effect. High pressure causes pressure to build up quickly, while the longer the pressure, the greater the risk of pressure buildup. In individuals at high risk of pressure injuries, frequent position changes are a primary policy for preventing pressure injuries. Experimental studies show that irreversible ischemia occurs when pressure is applied continuously for two hours or longer. The best method for reducing pressure in patients is repositioning. The literature indicates that while pressure injuries cannot be completely prevented, their incidence can be significantly reduced through evidence-based practices, particularly through assessment of at-risk patients, appropriate early nursing interventions, and preventive measures. Advances in the early detection of pressure injuries have been reported in the literature and primarily involve measuring inflammatory markers in anatomical regions to capture the first signs of tissue damage.

Inclusion Criteria:

• - If the patient is conscious, they must volunteer to participate in the study.
• For unconscious patients, a first-degree relative (mother, father, spouse, child) must agree to participate in the study.
• The patient's dependency level score on the Barthel Activities of Daily Living Index must be 90 or below (moderately dependent, severely dependent, completely dependent).
• The patient must not have developed a pressure injury.
• The patient must be meeting their daily calorie needs as determined by the nutrition team.
• There must be no contraindications to turning the patient to any side.
• Patients who are at low risk according to the pressure injury scale (15 points or above according to the Braden Risk Assessment Scale).
• The patient must not have an acute neurological problem.
• Patients with a GCS score above 7.

Exclusion Criteria:

• - If the patient is conscious, they do not consent to participate in the study.
• For unconscious patients, their first-degree relative does not consent to participate in the study.
• Patients with a Barthel Activities of Daily Living Index score above 90 (mildly dependent, fully independent).
• The patient has an existing pressure injury.
• The patient is not meeting their daily calorie needs as determined by the nutrition team.
• There is a contraindication to turning the patient to any side.
• Patients with moderate to high risk according to the pressure injury scale (score below 15 according to the Braden Risk Assessment Scale).
• The patient has an acute neurological problem.
• Patients with a GCS score of 7 or below.

In this study, individual patient data was used in an anonymized form and will not be shared with third parties in accordance with the principles of patient privacy and the protection of personal data.