This study aims to evaluate the effect of thyroid dysfunction on liver function tests.

Inclusion Criteria:

• All patients between the ages of 20-60 years old either with Hypothyroidism or Hyperthyroidism (controlled on treatment or not) and firstly diagnosed Hypothyroidism or Hyperthyroidism.
• Euthyroid controls (clinically healthy control subjects were recruited from the general population with the same socio-economic status with the subjects.)

Exclusion Criteria:

• Patients aged < 20 years old.
• Patients With Liver Disease.
• Pregnant and lactating women.
• Patients with severe infections or sepsis.
• Patients with Heart Disease.
• Patients who on drugs that can affect liver function such as phenothiazine, phenylbutazone, methyldopa, among others.

All patients between the ages of 20-60 years old either with Hypothyroidism or Hyperthyroidism (controlled on treatment or not) and firstly diagnosed Hypothyroidism or Hyperthyroidism.