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This clinical trial aims to study whether dual-target transcranial alternating current stimulation (tACS) applied to the auditory and motor brain region can improve repetition disorder in people with stroke, and to evaluate the safety of tACS. The main goals are to answer the following questions:
Researchers will compare the effects of real tACS versus sham (placebo) stimulation to see if real stimulation leads to better outcomes in aphasia patients.
Participants will:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| real group | Experimental | dual-target tACS on auditory and motor brain area at a frequency of 8 Hz,with individualized current intensity, delivered for 20 minutes. |
|
| sham group | Sham Comparator | sham tACS except for turning down the current intensity to zero during the 20-minute period, all other parameters are identical to those in real group. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| speech training | Behavioral | speech training(especially repetition training) synchronized with tACS stimulation |
|
| Measure | Description | Time Frame |
|---|---|---|
| Western Aphasia Battery (WAB) score | Western Aphasia Battery (WAB) score:0-100,higher score means better language function | Baseline and 10-days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen University | Guangzhou | Guangdong | China |
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| ID | Term |
|---|---|
| D001037 | Aphasia |
| ID | Term |
|---|---|
| D013064 | Speech Disorders |
| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
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| real tACS | Other | dual-target tACS on auditory and motor brain area at a frequency of 8 Hz,with individualized current intensity, delivered for 20 minutes. |
|
| sham tACS | Other | except for turning down the current intensity to zero during the 20-minute period, all other parameters are identical to those in real group. |
|
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |