Does Recessive Optic Atrophy Due to WFS1 Exist? | NCT07336966 | Trialant

Does Recessive Optic Atrophy Due to WFS1 Exist? | NCT07336966 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
wolfram syndrome		Patients according to the EuroWABB criterions of Wolfram syndrome and French national guidelines	Other: analyse study
recessive optic atrophy		patients with an OA due to mutation of gene WFS1, whatever its age of occurrence, without any other clinical manifestation.	Other: analyse study

Interventions

Name	Type	Description	Arm Group Labels	Other Names
analyse study	Other	Retrospective analyse and study of recorded data of patients with wolfram syndrome or recessive optic atrophy due to WFS1 mutation	recessive optic atrophy

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Visual acuity at the last visit	Comparison of visual acuity at the last visual between the 2 groups	The last visit will be registered regardless of the time elapsed since the onset of the disease, considered as a baseline

Secondary Outcomes

Measure	Description	Time Frame
Evolution of visual acuity	We only take in account the first visual assessments and the delay from the occurrence of the OA as well as the last visual assessment when possible and the delay between those two examinations.	Measurement at the occurence of the disease considered as baseline and at the last visit

Condition Browse Module